Compared With Different Method for Postcesarean Section Analgesia

Intraperitoneal Instillation and Wound Infiltration Compared With Intrathecal Morphine for Postcesarean Section Analgesia : A Prospective Randomized Controlled Double- Blind Trial

The aim of this study is compare the efficacy of local anesthetic infiltration into all layers of the anterior abdominal wall and peritoneal instillation and intrathecal injection of morphine with local anesthesic to reduce pain in women undergoing elective cesarean section under spinal anesthesia. The primary outcome is to compare the total amount of opioids consumed in the first 24 hours postoperatively.

Secondary purpose; Pain scores at 2,4,6,12,and 24 hours during movement ( moving back and forth in bed ) and rest ( lying motionless in bed )

This prospective randomized double-blind study will be planned on 46 pregnant women aged 18-50 who will undergo cesarean section with Pfannenstiel incision under spinal anesthesia with American Society of Anesthesiologists Classification (ASA) II,fullterm singular pregnancy after receiving the approval of the ethics committee of Ataturk University Medical Faculty Hospital and written approval of the patients

Inclusion Criteria:

• Pregnant women
• 18-50 age
• ASA II
• Fullterm singular pregnancy

Exclusion Criteria:

• Neuraxial anesthesia is contraindicated,
• Allergy to the drugs to be used in the study,
• Refused to participate in the study,
• BMI>35 kg/m2
• ASA≥3
• Diabetes
• Preeclampsia,
• Cardiovascular disease
• Chronic pain and neuropathic pain,
• Given opioids in the operation due to intraoperative pain,
• Switched to general anesthesia,
• Excessive bleeding during the operation,
• Uterine atony
• Drain placed in the area to be infiltrated,
• History of drug addiction and psychiatric illness,
• Understand Visual analog pain scale