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A retrospective cohort study of computed tomography scans of AAA patients considered for repair, in order to identify sex specific differences in abdominal aortic aneurysm (AAA) metrics and the association between anatomical differences/features of complexity and adverse patient outcome.
A retrospective cohort study of computed tomography scans of AAA patients considered for repair.
The study aims to, firstly, identify sex specific differences in abdominal aortic aneurysm (AAA) metrics utilising manual and automated image processing techniques; and secondly, if numbers are sufficient, explore the association between features of AAA complexity and adverse patient outcome.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Men | Male participants |
| |
| Women | Female Participants |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| CTA Aorta | Diagnostic Test | Computed Tomography Angiography - Aorta Whole |
|
| Measure | Description | Time Frame |
|---|---|---|
| Sex-specific differences in thrombus burden | Volumetric assessment of aortic thrombus | Pre-operative CT |
| Sex-specific differences in anatomical complexity | Anatomical as assessed by current IFU (instructions for use) criteria. (Anatomy within pre-specified vessel diameter, length, tortuosity and calcification criteria for insertion of endovascular stent graft for AAA repair.) | Pre-operative CT |
| Measure | Description | Time Frame |
|---|---|---|
| Association between anatomical differences and adverse patient outcome for patients receiving operative repair - need for transfusion, risk of vessel injury, ischaemia (bowel or limb), renal injury and re-intervention/endoleak. | Post-operative outcomes | 30 days |
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Inclusion Criteria:
Exclusion Criteria:
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Patients with AAA receiving assessment +/- primary open or endovascular repair.
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Imperial College London | London | United Kingdom |
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| ID | Term |
|---|---|
| D017544 | Aortic Aneurysm, Abdominal |
| ID | Term |
|---|---|
| D001014 | Aortic Aneurysm |
| D000783 | Aneurysm |
| D014652 | Vascular Diseases |
| D002318 | Cardiovascular Diseases |
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| D001018 |
| Aortic Diseases |