Clinical Efficacy of Ginkgo Biloba Extract in the Treatment of Knee Osteoarthritis

Clinical Efficacy of Ginkgo Biloba Extract in the Treatment of Knee Osteoarthritis

To assess the efficacy and safety of the Ginkgo biloba extract in patients with Knee OA.

Inclusion Criteria:

• patients 40-75 years old with knee OA.
• Grade II and Grade III according to the Kellgrenn-Lawrence (KL) grading system of radiographic OA.

Exclusion Criteria:

• Pregnancy, breastfeeding
• Liver or renal problems
• Patient taking any drug that might interact with Ginkgo extract (eg. warfarin, etc.)
• patient with cardiovascular or cerebral vascular disorders, uncontrolled diabetes, allergic to ginkgo, recent surgery or hospital admission, >75 years old.
• Allergic or contraindicated to using NSAIDs