Comparing the Pharmacological Profile of Formulations Containing Omega 3 Fatty Acids

Comparing the Pharmacological Profile of Enteric Coated and Non-Enteric Coated Capsules Containing Omega 3 Fatty Acids

The primary objective of this study is to investigate the uptake/gastrointestinal absorption of fatty acids in healthy adult volunteers by using enteric coated and non-enteric coated soft capsules containing omega 3 fatty acids. Pharmacokinetic parameters such as AUC and Cmax, as well as any adverse events are recorded.

As secondary objective, the short-term effects of Omega-3 supplementation on blood lipid parameters in healthy volunteers are evaluated using a Cholestech LDX analyzer to measure cholesterol and related lipids.

Inclusion Criteria:

• Age 21-65
• healthy, good physical condition

Exclusion Criteria:

• Pregnancy or breast-feeding
• Gastrointestinal conditions
• Acute or chronic liver disease
• Acute or chronic kidney disease
• Acute or chronic cardiovascular disease
• Allergy or Intolerance to gluten
• Allergy or Intolerance to fish or shellfish
• Use of medications (e.g., anticoagulants/ blood thinners such as warfarin; blood lipid-lowering agents such as statins)
• Use of Fish oil supplements
• Use of any form of nicotine or tobacco
• Alcohol and substance abuse history
• Participation in another investigational study