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We aim to compare three different radiation delivery techniques, namely three-dimensional conformal radiation therapy (3D-CRT), intensity modulated radiotherapy (IMRT) and volumetric modulated radiation therapy (VMAT) in left-sided early breast cancer patients.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| 3DCRT group | In this plan, we will create plans using three dimensional conformal radiotherapy, evaluate organs at risk doses, dose homogeneity and planned target volume coverage. Then compare these parameters with the two other plans. | ||
| IMRT group | In this plan, we will create plans using intensity modulated radiotherapy (IMRT), evaluate organs at risk doses, dose homogeneity and planned target volume coverage. Then compare these parameters with the two other plans. | ||
| VMAT plan | In this plan, we will create plans using volumetric modulated radiotherapy (VMAT), evaluate organs at risk doses, dose homogeneity and planned target volume coverage. Then compare these parameters with the two other plans. |
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| Measure | Description | Time Frame |
|---|---|---|
| Comparison of coverage of planned target volume(PTV) among the three plans. | PTV coverage in dose is compared among the three plans. | 1 year |
| Comparison of doses to organs at risk among the three plans. | mean dose of the heart, lung volume receiving 20Gy, esophageal doses will be compared among the three plans | 1 year |
| Measure | Description | Time Frame |
|---|---|---|
| Comparison of target homogeneity among the three plans. | 1 year |
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Inclusion Criteria:
Exclusion Criteria:
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30 Female patients who will present to clinical Oncology department with early breast cancer, with pathological staging ≤ T2N0M0 and are operated by conservative breast surgery will be included in our current study.
| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Alshaymaa Abdelghaffar, PhD | Contact | 01006828975 | 002 | alshimaaahmed@med.sohag.edu.eg |
| Emad Eldin Nabil Hassan, PhD | Contact | 01227014556 | 002 | emadd122@yahoo.com |
| Name | Affiliation | Role |
|---|---|---|
| Alshaymaa Abdelghaffar, PhD | Sohag University | Principal Investigator |
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| ID | Term |
|---|---|
| D001943 | Breast Neoplasms |
| ID | Term |
|---|---|
| D009371 | Neoplasms by Site |
| D009369 | Neoplasms |
| D001941 | Breast Diseases |
| D012871 | Skin Diseases |
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| D017437 |
| Skin and Connective Tissue Diseases |