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Background: The development of acute kidney injury (AKI) is an important indicator of clinical outcomes after cardiac surgery. Elevated preoperative hemoglobin A1c level may be associated with acute kidney injury in patients undergoing coronary artery bypass grafting. This study will investigate the association of preoperative HbA1c levels with AKI after isolated coronary artery bypass grafting (CABG).
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Pre-diabetic group | Patients with preoperative HbA1c 5.7-6.4% (group A) (prediabetics) |
| |
| Diabetic group | Patients with preoperative HbA1c > or = 6.5% till 7% or > 7% in case of emergency surgery or rapidly progressive cases with no time for long-term glycemic control (group B) (diabetics) |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| increase in serum creatinine | Diagnostic Test | any of the following: increase in serum creatinine by ≥ 0.3 mg/dl within 48 h of surgery or increase in serum creatinin |
|
| Measure | Description | Time Frame |
|---|---|---|
| serum creatinine level | increase in serum creatinine by ≥ 0.3 mg/dl within 48 h of surgery or increase in serum creatinine to ≥ 1.5 times baseline within 3 days of cardiac surgery | 3 days |
| Measure | Description | Time Frame |
|---|---|---|
| Patients in need of RRT | The number of patients requiring postoperative renal replacement therapy | 7 days |
| Measure | Description | Time Frame |
|---|---|---|
| Length of ICU stay | The duration of postoperative patient stay in the intensive care | 7days |
Inclusion Criteria:
Exclusion Criteria:
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This study compared the AKI incidence between patients with prediabetic level of HbA1c (5.7-6.4) and patients with elevated levels of HbA1c (> or = 6.5). Forty patients who underwent elective CABG were enrolled in this cohort study.
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Ain-Shams University | Cairo | Egypt |
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| ID | Term |
|---|---|
| D058186 | Acute Kidney Injury |
| ID | Term |
|---|---|
| D051437 | Renal Insufficiency |
| D007674 | Kidney Diseases |
| D014570 | Urologic Diseases |
| D052776 | Female Urogenital Diseases |
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| D005261 |
| Female Urogenital Diseases and Pregnancy Complications |
| D000091642 | Urogenital Diseases |
| D052801 | Male Urogenital Diseases |