Preoperative Level of Hemoglobin A1c and Acute Kindey Injury After Coronary Artery Bypass Grafting Surgery

Association Between Preoperative Level of Hemoglobin A1c and the Incidence of Acute Kindey Injury After Coronary Artery Bypass Grafting Surgery: a Cohort Study

Background: The development of acute kidney injury (AKI) is an important indicator of clinical outcomes after cardiac surgery. Elevated preoperative hemoglobin A1c level may be associated with acute kidney injury in patients undergoing coronary artery bypass grafting. This study will investigate the association of preoperative HbA1c levels with AKI after isolated coronary artery bypass grafting (CABG).

Inclusion Criteria:

• ASA physical status II-III
• scheduled to undergo isolated coronary artery bypass grafting

Exclusion Criteria:

• Patients with history of renal failure
• Patients with history of hepatic failure
• Patients with history of heart failure
• previous cardiac surgery
• cerebrovascular event in the last 30 days
• percutaneous coronary intervention in the last 30 days prior to operation
• peripheral arterial disease
• malignancy
• infectious diseases
• patients who required surgical revision
• patients who required postoperative intra-aortic balloon pump
• patients with CBP time > 120 min or aortic cross clamp time > 90 min