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Three-Dimensional Vascular Reconstruction of the Pancreas on Multi detector Computed Tomography images and its impact on patients undergoing Pancreatoduodenectomy - A Prospective Observational Study IPDA is difficult to identify in pre op in routine CECT images IPDA is difficult to identify in intra op Identification of those major blood vessels (SMA, MCA, Left Renal vein) that lie around the IPDA and then to measure the distances between these major vessels and the IPDA, helps to determine the location of the IPDA
Pancreaticoduodenectomy (PD) is a complex surgical procedure performed for benign and malignant indications .
Vascular anatomy of the pancreatic head, is important in multiple aspects
IPDA can be identified in up to 86% of the time using 3D MDCT . Identification of those major blood vessels (SMA, MCA, Left Renal vein) that lie around the IPDA and then to measure the distances between these major vessels and the IPDA, helps to determine the location of the IPDA.
In the existing studies, they have not defined the impact of identifying IPDA on intra operative parameters ( Operative time, Blood loss) These studies have not used uniform landmarks in the identification of IPDA
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Consecutive adult patients undergoing pancreaticoduodenectomy | All the consecutive patients who undergo pancreaticoduodenectomy will be recruited into the study after obtaining informed consent |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Pancreaticoduodenectomy | Procedure | In Pre Operative phase 64 Slice MD CT scan will be taken in all patients undergoing PD in pre op period 3D reconstruction of Peripancreatic vascular system using MDCT images Measure longitudinal distance between Root of Left renal vein, origin of IPDA Measure distance between origin of SMA , MCA and the IPDA In Intraoperative period Distance will be measured using standard disposable ruler from Root of Left renal vein to IPDA after Transection of Pancreas followed by specimen removal and to measure the distance between MCA, SMA and IPDA using standard disposable ruler . |
| Measure | Description | Time Frame |
|---|---|---|
| Probability of identifying IPDA with in 1 cm of anticipated location from Left renal vein determined by preoperative 3D reconstructed MDCT images. | During the procedure distance will be measured between root of Left Renal vein to Origin of IPDA | During the Procedure |
| Measure | Description | Time Frame |
|---|---|---|
| To correlate the location of IPDA predicted by 3D reconstruction of preoperative MDCT images with actual intraoperative location of MCA and SMA, after specimen removal | During the procedure distance will be measured between Origin of SMA and MCA to Origin of IPDA | During the Procedure |
| To correlate the early ligation of IPDA with Blood Loss and Operative time |
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Inclusion Criteria:
• Consecutive Patients undergoing pancreaticoduodenectomy during the study period at ILBS
Exclusion Criteria:
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Consecutive adult patients undergoing pancreaticoduodenectomy during the study period at ILBS
| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Manoj Kumar YL, MBBS, MS | Contact | 9164313430 | manojkumaryl91@gmail.com | |
| Piyush Kumar Sinha, MBBS,MS,MCh | Contact | 9540946821 | piyushkumarsinha@gmail.com |
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| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 28099958 | Background | Tomimaru Y, Tanaka K, Noguchi K, Hatano H, Eguchi H, Dono K. Distance from Left Renal Vein to Inferior Pancreaticoduodenal Artery: A Landmark for Identifying Inferior Pancreaticoduodenal Artery in Pancreatoduodenectomy. Dig Surg. 2017;34(4):335-339. doi: 10.1159/000453553. Epub 2017 Jan 19. | |
| 20714842 | Background |
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|
Blood Loss during the procedure and time required to complete the pancreaticoduodenectomy procedure |
| During the Procedure |
| Spectrum of arterial anomalies encountered during Pancreaticoduodenectomy | Anatomy of vascular arcades arising from the celiac and superior mesenteric arteries will be noted during the procedure | During The Procedure |
| To compare operative time between patients who undergo pre operative 3D vascular reconstruction on MD CT followed by Pancreaticoduodenectomy versus historical controls who have undergone pancreaticoduodenectomy at ILBS | Operative time of patients who have undergone pancreaticoduodenectomy during the study period is compared with historical cohorts | During the Procedure |
| To compare blood loss between patients who undergo pre operative 3D vascular reconstruction on MD CT followed by Pancreaticoduodenectomy versus historical controls who have undergone pancreaticoduodenectomy at ILBS | Blood loss of patients who have undergone pancreaticoduodenectomy during the study period is compared with historical cohorts | During the Procedure |
| Horiguchi A, Ishihara S, Ito M, Asano Y, Yamamoto T, Miyakawa S. Three-dimensional models of arteries constructed using multidetector-row CT images to perform pancreatoduodenectomy safely following dissection of the inferior pancreaticoduodenal artery. J Hepatobiliary Pancreat Sci. 2010 Jul;17(4):523-6. doi: 10.1007/s00534-009-0261-9. Epub 2010 Feb 9. |
| 24622068 | Background | Fang CH, Kong D, Wang X, Wang H, Xiang N, Fan Y, Yang J, Zhong SZ. Three-dimensional reconstruction of the peripancreatic vascular system based on computed tomographic angiography images and its clinical application in the surgical management of pancreatic tumors. Pancreas. 2014 Apr;43(3):389-95. doi: 10.1097/MPA.0000000000000035. |
| 20065548 | Background | Perwaiz A, Singh A, Singh T, Chaudhary A. Incidence and management of arterial anomalies in patients undergoing pancreaticoduodenectomy. JOP. 2010 Jan 8;11(1):25-30. |
| 8875875 | Background | Sim JS, Choi BI, Han JK, Chung MJ, Chung JW, Park JH, Han MC. Helical CT anatomy of pancreatic arteries. Abdom Imaging. 1996 Nov-Dec;21(6):517-21. doi: 10.1007/s002619900117. |
| 24434918 | Background | Patel BN, Giacomini C, Jeffrey RB, Willmann JK, Olcott E. Three-dimensional volume-rendered multidetector CT imaging of the posterior inferior pancreaticoduodenal artery: its anatomy and role in diagnosing extrapancreatic perineural invasion. Cancer Imaging. 2013 Dec 30;13(4):580-90. doi: 10.1102/1470-7330.2013.0051. |
| ID | Term |
|---|---|
| D016577 | Pancreaticoduodenectomy |
| ID | Term |
|---|---|
| D013505 | Digestive System Surgical Procedures |
| D013514 | Surgical Procedures, Operative |
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