Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Cognitive impairment is one of the core early signs of dementia, and it is also a key stage for community-based dementia prevention. Accurate and convenient prediction of cognitive impairment can help the community to identify and manage the high-risk population of dementia. Previous studies had developed several dementia predicting models, but such models may be not suitable for cognitive impairment prediction. Based on the national representative follow-up data of Chinese Longitudinal Healthy Longevity Survey (CLHLS), this project aims to develop and validate a brief cognitive impairment prediction algorithm among the community-dwelling elderly, using machine learning methods (such as Logistic regression, Naïve Bayes model, Extreme Gradient Boosting Tree and so on). Finally, based on the constructed model, an easy-to-use online intelligent assessment tool for predicting cognitive impairment risk will be developed. The general practitioners, social workers and the elderly would be invited to use the tool and we will revise the tool according to their suggestions and comments. This project is expected to provide scientific basis and technical support for community-based dementia prevention, and will also be useful for the elderly to easily understand their cognitive health.
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Training cohort | The training cohort will be used for model development. | ||
| Testing cohort | The testing cohort, a new cohort compared with the training cohort, will be used for model external validation. |
Not provided
| Measure | Description | Time Frame |
|---|---|---|
| AUC | the AUC of the prediciton model based on the test data | an average of 3 years after baseline assessement |
| Measure | Description | Time Frame |
|---|---|---|
| sensitivity | the sensitivity of the prediciton model based on the test data | an average of 3 years after baseline assessement |
| specificity | the specificity of the prediciton model based on the test data |
Not provided
Inclusion Criteria:
Exclusion Criteria:
Not provided
Not provided
Not provided
The study population of this project was those community-dwelling older adults with normal cognitive function at baseline and completed cognitive function assessment three years later.
Not provided
| Name | Affiliation | Role |
|---|---|---|
| Feifei Gao, Ph.D | Peking University Six Hospital | Study Director |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Peking University Six Hospital | Beijing | 100191 | China |
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
| ID | Term |
|---|---|
| D060825 | Cognitive Dysfunction |
| ID | Term |
|---|---|
| D003072 | Cognition Disorders |
| D019965 | Neurocognitive Disorders |
| D001523 | Mental Disorders |
Not provided
Not provided
Not provided
Not provided
Not provided
| an average of 3 years after baseline assessement |
| positive predictive value | the positive predictive value of the prediciton model based on the test data | an average of 3 years after baseline assessement |
| negative predictive value | the negative predictive value of the prediciton model based on the test data | an average of 3 years after baseline assessement |