Safety and Efficacy of Two Oral Tinidazole Regimens for Refractory Trichomonas Vaginitis

Oral Tinidazole Treatment of Refractory Trichomonas Vaginitis

We compare two oral tinidazole regimens for refractory trichomonas vaginitis.

Refractory trichomonas vaginitis has become a clinical problem, which has a direct impact on the health and life of patients. Refractory trichomonas vaginitis is mainly caused by drug resistance of trichomonas. Drug resistant trichomonas has appeared China. Increasing the dosage of anti trichomonal drugs is the main treatment method at present. The aim of this study was to evaluate the efficacy and safety of two oral tinidazole regimens for refractory trichomonas vaginitis.

Inclusion Criteria:

• Women be at least 18 years of age
• Failure of conventional treatment (recommended by guidelines including tinidazole, 2g once daily for 5-7 days)

Exclusion Criteria:

• Allergy to metronidazole or tinidazol
• Pregnant or nursing
• HIV or other chronic disease