The goal of this substudy (main study NCT04498585) is to determine the feasibility of applying virtual reality stimulation to patients in the intermediate care unit. Patients on this ward are generally more awake and alert than patients in the intensive care unit, thereby they are able to provide feedback about their experience. As the intermediate care unit is not without stress, examining the physiological parameters (e.g., heart rate, respiration rate, blood pressure, etc.) could also provide telling information as to the calming effect of virtual reality. The movements of these patients are also recorded using accelerometers which will provide valuable information about the characteristics of the movements that patients make while confined to their beds. These movements can act as a reference for further investigation into movements related to delirium which is a secondary outcome measure of the main study.

Inclusion Criteria:

• Written informed consent
• Aged ≥18 years
• No severe visual or auditory impairments (strabismus, macular degeneration, retinopathy)
• German or French speaking
• Estimated length of stay (from time of study inclusion) >24 hours

Exclusion Criteria:

• Patients without calotte, with external ventricular drainage or other Intracranial pressure probes
• Patients with epilepsy
• Patients with Covid-19

The investigators will ask patients to provide informed consent for sharing their anonymized data. Once the study results are published, the investigators will make the de-identified study dataset available for secondary analyses by sharing the dataset upon reasonable request.

Data will be shared once study results have been published.

To be determined.