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Subjects will walk on a treadmill at 3 mph and sweat will be collected from both forearms. One arm will be pretreated with topical lidocaine, and the other will act as the control.
Subjects will walk on a treadmill at 3 mph and sweat will be collected from both forearms. One arm will be pretreated with topical lidocaine, and the other will act as the control. Sweat will be collected via macroducts attached to each arm. Sweat production on each arm will be compared using t-tests.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| lidocaine pretreated skin | Experimental | one arm will be pretreated with lidocaine before exercise in the heat |
|
| control skin | No Intervention | the other arm will act as the control condition |
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Lidocaine | Drug | effect of lidocaine on sweat production during exercise in the heat |
|
| Measure | Description | Time Frame |
|---|---|---|
| volume of sweat produced during exercise following topical lidocaine | Volume of sweat produced during exercise following tipocal lidocaine | one hour of exercise |
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Inclusion Criteria: 18-35 years of age -
Exclusion Criteria: pregnant females
-
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| Name | Affiliation | Role |
|---|---|---|
| Michael J Buono | San Diego State University | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| San Diego State University | San Diego | California | 92120-1805 | United States |
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| ID | Term |
|---|---|
| D009043 | Motor Activity |
| ID | Term |
|---|---|
| D001519 | Behavior |
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| ID | Term |
|---|---|
| D008012 | Lidocaine |
| ID | Term |
|---|---|
| D000083 | Acetanilides |
| D000813 | Anilides |
| D000577 | Amides |
| D009930 | Organic Chemicals |
| D000814 |
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| control | Other | one arm will be pretreated with topical lidocaine, the other arm will not |
|
| Aniline Compounds |
| D000588 | Amines |