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Impact of Intraoperative Spraying methylene blue In thyroidectomy
General anaesthesia ,supine position with hyperextension to the neck Low collar incision to the neck , incision to the skin and platysma muscle and fascia ,upper and lower flaps are developed ,separation of strap muscles and identification of the thyroid gland after freeing of investing fascia Ligation of the middle thyroid vein and ligation and separation of the superior pedicle away from the external laryngeal nerve At this point of operation and before ligation of inferior pedicle, methylene blue 0.05% spraying is applied to the field the amount varies according to size of the thyroid lobe and variation in population and neck size Thyroid gland stained by bluish color , recurrent laryngeal nerve not stained or minimally stained so we can avoid injury to it parathyroid glands get red of the stain after about 3 minutes so we can avoid injury to it thyroid gland lose its stain in about 15 minutes so we can remove any residual and decrease residual tissue or recurrence
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Intraoperative Spraying Methylene Blue In Thyroidectomy | Experimental |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Impact of Intraoperative Spraying Methylene Blue In Thyroidectomy | Procedure | General anaesthesia ,supine position with hyperextension to the neck Low collar incision to the neck , incision to the skin and platysma muscle and fascia ,upper and lower flaps are developed ,separation of strap muscles and identification of the thyroid gland after freeing of investing fascia Ligation of the middle thyroid vein and ligation and separation of the superior pedicle away from the external laryngeal nerve At this point of operation and before ligation of inferior pedicle methylene blue 0.05% spraying is applied to the field the amount varies according to size of the thyroid lobe and variation in population and neck size Thyroid gland stained by bluish color , recurrent laryngeal nerve not stained or minimally stained so we can avoid injury to it parathyroid glands get red of the stain after about 3 minutes so we can avoid injury to it thyroid gland lose its stain in about 15 minutes so we can remove any residual and decrease residual tissue or recurrence |
| Measure | Description | Time Frame |
|---|---|---|
| Recurrent laryngeal nerve injury | 2 weeks | |
| Parathyroid gland Injuries | 3 months | |
| Intraoperative injury to trachea | 2 weeks | |
| Operative time | 1 day | |
| Presence of residual or recurrence | 3 months |
| Measure | Description | Time Frame |
|---|---|---|
| Hoarseness of voice | temporary or permanent (by clinical evaluation and vocal cord examination) | 3 months |
| Stridor | temporary or permanent (by clinical evaluation and vocal cord examination) |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Mohamed Ahmed Orabi, Specialist Surgical Oncology | Contact | +2 01001868637 | Mohamedorabi5885@gmail.com | |
| Amr M Makky, Specialist Surgical Oncology | Contact | +2 010222339139 | Amr.mostafa.makky@gmail.com |
| Name | Affiliation | Role |
|---|---|---|
| Remon Elia Lukas, Specialist Surgical Oncology | Qena Oncology Center | Study Director |
| Mohamed Taha Mousa, Resident Surgical Oncology | Qena Oncology Center | Study Director |
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Impact of Intraoperative Spraying methylene blue thyroidectomy
about 1year
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| ID | Term |
|---|---|
| D013965 | Thyroidectomy |
| ID | Term |
|---|---|
| D013507 | Endocrine Surgical Procedures |
| D013514 | Surgical Procedures, Operative |
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Impact of Intraoperative Spraying Methylene Blue In Thyroidectomy
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|
| 3 months |
| Hypoparathyroidism | temporary or permanent (level of para thormone hormone ) | 3 months |
| Hypocalcaemia | temporary or permanent ( level of total and free serum calcium ) | 3 months |
| Mina Romany Tawfeek, Specialist General Surgery |
| Qena Oncology Center |
| Study Director |
| Abdullah Atyah Ali, Ass.Lecture General Surgery | Qena Oncology Center--Luxor University | Study Director |
| Ali Hassan, Resident General Surgery | Qena Oncology Center --Qena University | Study Chair |
| Mohamed Ahmed Orabi, Specialist Surgical Oncology | Qena Oncology Center | Principal Investigator |
| Amr M Makky, Specialist Surgical Oncology | Qena Oncology Center- Medical Military Academy | Study Director |
| Mostafa Sayedd Abd el Rahaman, Resident Surgical Oncology | Qena Oncology Center | Study Chair |
| Mena Zarief Malaty, Resident General Surgery | Qena Oncology Center--Nag hammady Hospital | Study Chair |
| Hussein El Lithy, Resident General Surgery | Qena Oncology Center--Qena General Hospital | Study Chair |
| Abobakr Mohammed, Resident General Surgery | Qena Oncology Center--Qena General Hospital | Study Chair |
| Mohamed Mahmoud El Zeer, Resident General Surgery | Qena Oncology Center- Sohag University | Study Chair |
| Mahmoud Rabeea Ahmed, Resident General Surgery | Qena Oncology Center-Aswan University | Study Chair |
| Mohamed Abouelmagd Salem, Prof. Surgical Oncology | Qena Oncology Center-ٍSouth Egypt Center Institute Assiut University | Study Chair |
| Mohamed Saeed Ayaty, Ass.Prof. Surgical Oncology | Qena Oncology Center-National Cancer Institute Cairo University | Study Chair |
| Mohamed H Mahran, Ass.Prof. Surgical Oncology | Qena Oncology Center-ٍSouth Egypt Center Institute Assiut University | Study Chair |
| Mohamed Hasan Abdel-Aal, Director of QOC | Qena Oncology Center | Study Chair |