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| Name | Class |
|---|---|
| Medicbook LLC | UNKNOWN |
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The Clinical Decision Support Systems (CDSS) based on real clinical data and its own algorithms can help to make the right choice according to guidelines. The goal of the INTELLECT II study is to investigate treatment adherence to guidelines/science-based medicine and its impact on patient outcomes into two groups of doctors, clinical centers with standard care of treatment (control), and clinical centers using CDSS (active).
Hypertension and atrial fibrillation are 2 important public health priorities. There is a gap between evidence-based best management and actual clinical practice. To decrease this gap, clinical practice guidelines (CPGs), based on available evidence are employed. Clinical decision support system ("MedicBK") is a computer-based program that analyzes published evidence and provides prompts and reminders to assist health care providers in implementing clinical guidelines and science-based medicine at the point of care. The INTELLECT II trial is designed as a multicenter, cluster-randomized, single-blind, controlled study with blinded outcome assessment. Approximately 10 centers from Russia will be enrolled. Centers managing patients with symptomatic atrial fibrillation and/or hypertension will be randomized to either patient management with aid of CDSS ("MedicBK") or standard care.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| CDSS | Active Comparator | patient management with aid of CDSS |
|
| standart care | No Intervention | patient management with standard care according to guidelines |
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| CDSS ("MedicBK") | Other | Clinical decision support system ("MedicBK") is a computer-based program that analyzes published evidence and provides prompts and reminders to assist health care providers in implementing clinical guidelines and science-based medicine at the point of care. |
| Measure | Description | Time Frame |
|---|---|---|
| Compliance with AF/hypertension clinical practice guidelines | number of patients treated in accordance with current ESC clinical guidelines for management atrial fibrillation evaluated by independent professionals compared with Clinical decision support system MedicBK | 1 month |
| Measure | Description | Time Frame |
|---|---|---|
| Total cardiovascular events | total stroke or systemic embolism, total coronary heart disease, major bleeding, recurrence of atrial fibrillation, hospitalization or death from congestive heart failure and other significant vascular deaths | 6 months |
| Total mortality |
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Inclusion Criteria:
Exclusion Criteria:
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Samara Regional Cardiology Dispansery | Samara | 443070 | Russia |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| Result | Duplyakov D.V., Shebonkina D.A., Uranov A.E., Mikheenko I.L., Astrakova K.S., Gartung A.A., Adonina E.V., Tukhbatova A.A., Kuzmin V.P., Fedorova G.A., Gabidullova D.A., Skuratova M.A., Shechovtsova T.A., Losik D.V. Optimizing compliance with clinical guidelines using a clinical decision support system in patients with hypertension and atrial fibrillation in real-world practice: a cluster-randomized comparative study INTELLECT-2. Russian Journal of Cardiology. 2025;30(12):6365. (In Russ.) https://doi.org/10.15829/1560-4071-2025-6365. EDN: OKIRDC |
| Label | URL |
|---|---|
| Related Info | View source |
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multicenter, cluster-randomized, single-blind, controlled study with blinded outcome assessment.
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|
death from all causes |
| 6 months |
| total number of non-planing visits and hospitalization | non-planing hospitalizations, non-planning visits, urgent visits | 6 months |
| ID | Term |
|---|---|
| D001281 | Atrial Fibrillation |
| D006973 | Hypertension |
| ID | Term |
|---|---|
| D001145 | Arrhythmias, Cardiac |
| D006331 | Heart Diseases |
| D002318 | Cardiovascular Diseases |
| D010335 | Pathologic Processes |
| D013568 | Pathological Conditions, Signs and Symptoms |
| D014652 | Vascular Diseases |
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