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| ID | Type | Description | Link |
|---|---|---|---|
| IRAS 264198 | Other Identifier | Health Research Authority (HRA) |
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| Name | Class |
|---|---|
| UCL, Bloomsbury and East London (UBEL) Doctoral Training Partnership | UNKNOWN |
| Economic and Social Research Council, United Kingdom | OTHER |
| University College London Hospitals | OTHER |
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Pregnancy care typically assumes patients are heterosexual married women whose gender matches their assigned sex (i.e., cisgender), stigmatizing patients and creating limitations, blocking affirming care. Consequently, lesbian, gay, bisexual, queer, intersex, asexual, and/or transgender (LGBTQIA+) parents face minority stress as discrimination in antenatal care. This mixed-methods study assesses stressors and resilience factors on pregnancy and birth outcomes. LGBTQIA+ pregnant parents (n=200) are case-matched with cisheterosexual peers (n=600). Primary data comes from two panel surveys, one antenatally and one postpartum, combined with medical records. A sub-sample (n=30) will complete a journal between surveys. Findings will inform care guidelines and provider training.
Patients using reproductive health services, like care during pregnancy (called antenatal care), are most often assumed to be heterosexual married women whose gender matched their sex assigned at birth (i.e., cisgender). Due to these assumptions, pregnancy care procedures are based on a sweeping assumption of who becomes pregnant and gives birth. This assumption is based on the pregnant person's gender and/or sexual orientation. As a result of this assumption, parents who are lesbian, gay, bisexual, queer, intersex, asexual, non-binary, and/or transgender (LGBTQIA+) can experience stress in the form of stigma, prejudice, and discrimination (i.e. "minority stress"). In the United Kingdom, there are 525,000 LGBTQIA+ potential gestational patients who may face this type of stress while receiving pregnancy care. That means that there is a preventable higher risk for pregnancy and birth complications caused by increased stress during pregnancy and daily life. These complications include macrosomia, pre-term birth, and low-birth weight. Preventable stress, also called minority stress, links to this increase in health problems outside of pregnancy as well. Since minority stress influences patient/parents' health, it is also called a risk or vulnerability. Resilience, or the ability to overcome stress and discrimination, can sometimes help improve health outcomes. However, little is known about which types of resilience can be helpful for LGBTQIA+ parents given their unique experiences of minority stress.
The planned observational study will investigate the ways in which experiences of minority stress and resilience in pregnancy care are associated with parent health and birth outcomes. A sample of pregnant patients (N=800) from maternity wards in and around London will take part through an online panel survey (completed twice) that will be linked to each patient/participant's electronic health records to create a quantitative dataset. Participant recruitment will focus on LGBTQIA+ pregnant patients (n=200). A matched comparison sample of cisgender, heterosexual pregnant patients (n=600) will also be recruited to take part from the same maternity. From the full sample, patient/parents from University College London Hospital will be invited to complete an at-home journal activity which will provide qualitative data on their experiences of minority stress and resilience. This smaller group (n=30). Results from this study can be used to inform LGBTQIA+ guidelines, training, and help make reproductive healthcare more inclusive.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Gestational parents | The study is composed of a sample of LGBTQIA+ and cisgender, heterosexual parents who are receiving antenatal care at the participating hospitals. |
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| Measure | Description | Time Frame |
|---|---|---|
| Primary Scientific Aim - Parental Health | The outcome measured for impact from resilience and vulnerability is parent health as allostatic load (as health data from routine antenatal check-ups). Scales will be composited into intrapersonal stressors (i.e., felt stigma, level of outness), interpersonal stressors (i.e., homelessness & child welfare, stressful life events/stress, everyday discrimination, chronic strains, police interactions), structural stressors (i.e., household social vulnerability index, deprivation score), intrapersonal resilience (i.e., coping, social support), interpersonal resilience (i.e., patient experience scale, shared decision-making, emotional reactivity), and structural resilience (i.e., community connectedness, civic engagement). | through study completion, up to 10 months |
| Primary Scientific Aim - Infant Health | The composite for parent health (i.e. allostatic load from Outcome 1) will be assessed to see if there is an impact on infant health (a composite of head circumference, gestational length, birth weight, birth length, Apgar score). | through study completion, up to 10 months |
| Measure | Description | Time Frame |
|---|---|---|
| Secondary Scientific Aim - Understanding additional stressors and resilience | Qualitative journals will be used to assess for additional stressors and resilience resources to ascertain if there are measures that have not been accounted for within the quantitative measures. These are presently unknown, as the point of the measure is to uncover these dimensions of the constructs of resilience and vulnerability. |
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Inclusion Criteria:
Exclusion Criteria:
Pregnant people of all genders are welcome to participate within the study as long as they are receiving antenatal care at a participating Hospital Trust.
Gestational parents receiving antenatal care in Greater London.
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| Name | Affiliation | Role |
|---|---|---|
| David M Frost, PhD | University College, London | Study Chair |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| King's College Hospital NHS Foundation Trust | Brixton | SW9 8RR | United Kingdom | |||
| Kingston Hospital NHS Foundation Trust |
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| King's College Hospital NHS Trust | OTHER |
| University Hospitals Sussex NHS Foundation Trust | OTHER_GOV |
| Homerton University Hospital | UNKNOWN |
| Barts & The London NHS Trust | OTHER |
| The Whittington Hospital NHS Trust | OTHER_GOV |
| Guy's and St Thomas' NHS Foundation Trust | OTHER |
| West Hertfordshire Hospitals NHS Trust | OTHER |
| Kingston Hospital NHS Trust | OTHER |
| Royal Free Hospital NHS Foundation Trust | OTHER |
| Imperial College Healthcare NHS Trust | OTHER |
| Epsom and St Helier University Hospitals NHS Trust | OTHER |
| Lewisham and Greenwich NHS Trust | OTHER_GOV |
| St George's University Hospitals NHS Foundation Trust | OTHER |
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| through study completion, up to 10 months |
| Secondary Scientific Aim - Contextualising resilience and vulnerability | The same qualitative journals in outcome 3 will also provided narratives about the experiences of parents with extreme resilience and vulnerability scores. The assessment of these narratives will be done to help contextualise the presence of extreme scores for parents receiving antenatal care at UCLH. The contents of these narratives collectively will be reported within the final findings alongside the quantitative data, as well as will be quoted specifically when relevant. | through study completion, up to 10 months |
| Kingston upon Thames |
| KT2 7QB |
| United Kingdom |
| Barts Health NHS Trust | London | E1 2EF | United Kingdom |
| Homerton University Hospital NHS Foundation Trust | London | E9 6SR | United Kingdom |
| Whittington Health NHS Trust | London | NW1 0PE | United Kingdom |
| Royal Free London NHS Foundation Trust | London | NW3 2QG | United Kingdom |
| Lewisham and Greenwich NHS Trust | London | SE13 6LH | United Kingdom |
| St George's University Hospitals NHS foundation Trust | London | SW17 0RE | United Kingdom |
| University College London Hospital NHS Foundation Trust | London | W1T 7DN | United Kingdom |
| Imperial College Healthcare NHS Trust | London | W2 1NY | United Kingdom |
| Guy's and St Thomas' NHS Foundation Trust | London | United Kingdom |
| Epsom and St Helier University Hospitals NHS Trust | Sutton | United Kingdom |
| West Hertfordshire Teaching Hospitals NHS Trust | Watford | WD18 0HB | United Kingdom |
| University Hospitals Sussex NHS Foundation | Worthing | BN11 2DH | United Kingdom |