Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
The purpose is to compare the efficacy of combined regional nasal block and general anesthesia versus general anesthesia with dexmedetomidine during endoscopic sinus surgery in optimizing intraoperative surgical field.
This study will be done to compare between two different techniques including regional nasal block and dexmedetomidine in optimizing intraoperative surgical field according to average category scale
Not provided
Not provided
Not provided
Not provided
Not provided
| Label | Type | Description | Intervention Names |
|---|---|---|---|
| regional nasal block | Active Comparator | sphenopalatine ganglion block with general anesthesia |
|
| dexmedetomidine | Active Comparator | use the drug with general anesthesia |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Bupivacaine HCl 0.5% Injectable Solution | Drug | using nasal block including sphenopalatine ganglion block with general anesthesia to optimize surgical field |
|
| Measure | Description | Time Frame |
|---|---|---|
| Optimizing intraoperative surgical field | Comparison between efficacy of the two techniques in optimizing intraoperative surgical field which will be measured using the average category scale(where grade 0 is defined as no bleeding and grade 5 is defined as severe bleeding, constant suctioning required). | Up to 6 months |
| Measure | Description | Time Frame |
|---|---|---|
| Heart rate in beat per minute | The heart rate will be measured in (beat/minute) at the commencement of surgery and at each assessment of the surgical field. The average mean values during the surgical procedures will be calculated in each group. | Up to 8 months |
| Blood loss in millilitres |
Not provided
Inclusion Criteria:
Exclusion Criteria:
Not provided
Not provided
Not provided
Not provided
| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Moustafa At Moustafa Hamouda, Ass lecturer | Contact | +201061123460 | moustafaatef.13b@gmail.com | |
| Rehab Ab Abdelrazik Elsayed, Lecturer | Contact | +201110108610 | rehab.fattah2002@gmail.com |
| Name | Affiliation | Role |
|---|---|---|
| Nahed Effat Yossef Salama, Professor | Ain Shams University | Study Chair |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Moustafa Rakha | Recruiting | Cairo | 0200 | Egypt |
comparison between the two techniques in optimizing surgical field
1 year
all collected IPD
Not provided
| ID | Term |
|---|---|
| D002045 | Bupivacaine |
| D020927 | Dexmedetomidine |
| ID | Term |
|---|---|
| D000813 | Anilides |
| D000577 | Amides |
| D009930 | Organic Chemicals |
| D000814 | Aniline Compounds |
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
|
| Dexmedetomidine | Drug | using dexmedetomidine with induction of general anesthesia to optimize surgical field |
|
Blood loss will be measured in millilitres as that collected in the suction apparatus and by weight of the nasal swabs. |
| Up to 8 months |
| endtidal sevoflurane concentration in MAC% | Endtidal sevoflurane concentration will be used as an indicator of inhaled anaesthetic dose. Mean end-tidal sevoflurane concentration will be calculated for each patient as the average of all concentrations recorded will be measured in MAC% | Up to 8 months |
| phentolamine requirements in milligrams | The total dose of additional hypotensive agent (phentolamine) requirements will be measured in milligrams | Up to 8 months |
| Duration of anesthesia in minutes | Duration of anesthesia will be measured in minutes | Up to 8 months |
| Pain assessment with visual analogue scale(VAS) | Pain intensity will be measured with a 10-cm visual analogue scale (where 0 is defined as no pain at all and 10 as the worst possible pain) at 2, 6 and 12 hours postoperatively. | Up to 8 months |
| Mean blood pressure in mmHg | The mean blood pressure will be measured in mmHg at the commencement of surgery and at each assessment of the surgical field. The average mean values during the surgical procedures will be calculated in each group. | Up to 8 months |
| Duration of surgery in minutes | Duration of surgery will be measured in minutes | Up to 8 months |
| D000588 |
| Amines |
| D007093 | Imidazoles |
| D001393 | Azoles |
| D006573 | Heterocyclic Compounds, 1-Ring |
| D006571 | Heterocyclic Compounds |