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Evaluation of safety and PK interaction between D-0120 and Alopurinol in healthy adult subjects
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| D-0120 plus Allopurinol | Experimental | D-0120 dosing followed by Allopurinol and combination treatment |
|
| Allopurinol plus D-0120 | Experimental | Allopurinol dosing followed by D-0120 and combination treatment |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| D-0120 in combination with Allopurinol | Drug | noted above |
|
| Measure | Description | Time Frame |
|---|---|---|
| Type, incidence, severity and attribution of AEs. | Evaluation of safety between D-0120 and Allopurinol | 14 days |
| Plasma concentration of D-0120 and Allopurinol | Evaluation of exposure between D-0120 and Allopurinol | 14 days |
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Inclusion Criteria:
Exclusion Criteria:
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Spaulding Clinical | West Bend | Wisconsin | 53095 | United States |
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| ID | Term |
|---|---|
| D000493 | Allopurinol |
| ID | Term |
|---|---|
| D011687 | Purines |
| D006574 | Heterocyclic Compounds, 2-Ring |
| D000072471 | Heterocyclic Compounds, Fused-Ring |
| D006571 | Heterocyclic Compounds |
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D0120 Allopurinol
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