Not provided
| ID | Type | Description | Link |
|---|---|---|---|
| 5R18HS026169 | U.S. AHRQ Grant/Contract | View source |
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
| Name | Class |
|---|---|
| Agency for Healthcare Research and Quality (AHRQ) | FED |
Not provided
Not provided
Not provided
Not provided
The objective of the study is to determine if Obstetric Life Support Program (OBLS) has an effect on the confidence and skills knowledge in participants.
Enrolled participants with healthcare experience will be randomized to intervention with an electronic curriculum and instructor-led course or placebo first and then will be crossed over to receive the intervention. Participants will undergo assessments pre and post intervention, as well as repeat assessments after three washout periods separated by six months each.
Not provided
Not provided
Not provided
Not provided
| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Curriculum and Instructor-Led Course | Active Comparator | Participants first complete an online cognitive assessment. Once complete, staff email the electronic curriculum for participants to read. On a specific day, participants will go to the designated center to participate in an instructor-led course and simulated medical scenarios and complete megapode and online cognitive assessment. After a washout period of six months, participants return to the designated center to participate in simulated medical scenarios and complete the online cognitive assessment again. After a second washout period of six months, participants will take the online cognitive assessment again. |
|
| Placebo | Placebo Comparator | On a specific day, participants will go to a designated center to complete an online cognitive assessment and participate in simulated medical scenarios. Once complete, study staff will email the electronic curriculum for participants to read. After a washout period of six months, participants will return to the designated center to participate in an instructor-led course and simulated medical scenarios and complete a megapode and online cognitive assessment. After a second washout period of six months, participants will take an online cognitive assessment again. |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Electronic curriculum and instructor-led course, then placebo | Other | Electronic curriculum and instructor-led course |
|
| Measure | Description | Time Frame |
|---|---|---|
| Change from Baseline in the Mean Participant Knowledge Assessment | Mean (standard deviation) of participant knowledge assessment scores post-training stratified by treatment arm. Minimum value is zero and maximum value is 100. A higher score means a better outcome. | From baseline to immediately upon completing training |
| Comparison of Scores Between Two Arms | Mean (standard deviation) of participant megacode checklist scores post-training stratified by treatment arm. Minimum value is zero and maximum value is 200. A higher score means a better outcome. | Immediately upon completing training |
| Measure | Description | Time Frame |
|---|---|---|
| Self-Reported Confidence Level in Assessing and Managing Critical Care Scenarios in Pregnant Patients | Frequency (percent) of participants who self-report that they are confident or very confident in managing procedures in pregnant patients. | From baseline to 6 months |
| Self-Reported Confidence Level in Assessing and Managing Critical Care Scenarios in Pregnant Patients |
Not provided
Inclusion Criteria:
PH
IH
Exclusion Criteria:
Not provided
Not provided
Not provided
Not provided
Not provided
| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Laurie Kavanagh, MPH | Contact | 206-399-0531 | kavanagh@uchc.edu | |
| Sheila Thurlow, MSN | Contact | 860-679-4637 | thurlow@uchc.edu |
| Name | Affiliation | Role |
|---|---|---|
| Andrea Shields, MD | UConn Health | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| UConn Health | Recruiting | Farmington | Connecticut | 06030 | United States |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 31575778 | Background | Collier AY, Molina RL. Maternal Mortality in the United States: Updates on Trends, Causes, and Solutions. Neoreviews. 2019 Oct;20(10):e561-e574. doi: 10.1542/neo.20-10-e561. | |
| 25979616 | Background | Hameed AB, Lawton ES, McCain CL, Morton CH, Mitchell C, Main EK, Foster E. Pregnancy-related cardiovascular deaths in California: beyond peripartum cardiomyopathy. Am J Obstet Gynecol. 2015 Sep;213(3):379.e1-10. doi: 10.1016/j.ajog.2015.05.008. Epub 2015 May 13. |
| Label | URL |
|---|---|
| Related Info | View source |
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
| Type | Date | Date Unknown |
|---|---|---|
| Release | Mar 13, 2024 | |
| Reset | Aug 16, 2024 | |
| Release | Sep 1, 2025 |
Not provided
The investigators will perform a prospective, single-blinded randomized cross-over trial of the OBLS intervention.
Not provided
Not provided
Megacode evaluators will be masked to the arm in which the participants are randomized.
| Placebo, then electronic curriculum and instructor-led course | Other | Electronic curriculum and instructor-led course |
|
Frequency (%) of participants who self-report that they are confident or very confident in managing procedures in pregnant patients. |
| From baseline to 12 months |
| 28383382 | Background | Briller J, Koch AR, Geller SE; Illinois Department of Public Health Maternal Mortality Review Committee Working Group. Maternal Cardiovascular Mortality in Illinois, 2002-2011. Obstet Gynecol. 2017 May;129(5):819-826. doi: 10.1097/AOG.0000000000001981. |
| 26443610 | Background | Jeejeebhoy FM, Zelop CM, Lipman S, Carvalho B, Joglar J, Mhyre JM, Katz VL, Lapinsky SE, Einav S, Warnes CA, Page RL, Griffin RE, Jain A, Dainty KN, Arafeh J, Windrim R, Koren G, Callaway CW; American Heart Association Emergency Cardiovascular Care Committee, Council on Cardiopulmonary, Critical Care, Perioperative and Resuscitation, Council on Cardiovascular Diseases in the Young, and Council on Clinical Cardiology. Cardiac Arrest in Pregnancy: A Scientific Statement From the American Heart Association. Circulation. 2015 Nov 3;132(18):1747-73. doi: 10.1161/CIR.0000000000000300. Epub 2015 Oct 6. |
| 1599071 | Background | Goodwin AP, Pearce AJ. The human wedge. A manoeuvre to relieve aortocaval compression during resuscitation in late pregnancy. Anaesthesia. 1992 May;47(5):433-4. doi: 10.1111/j.1365-2044.1992.tb02228.x. |
| 21549495 | Background | Jeejeebhoy FM, Zelop CM, Windrim R, Carvalho JC, Dorian P, Morrison LJ. Management of cardiac arrest in pregnancy: a systematic review. Resuscitation. 2011 Jul;82(7):801-9. doi: 10.1016/j.resuscitation.2011.01.028. Epub 2011 May 6. |
| 24781570 | Background | Lipman S, Cohen S, Einav S, Jeejeebhoy F, Mhyre JM, Morrison LJ, Katz V, Tsen LC, Daniels K, Halamek LP, Suresh MS, Arafeh J, Gauthier D, Carvalho JC, Druzin M, Carvalho B; Society for Obstetric Anesthesia and Perinatology. The Society for Obstetric Anesthesia and Perinatology consensus statement on the management of cardiac arrest in pregnancy. Anesth Analg. 2014 May;118(5):1003-16. doi: 10.1213/ANE.0000000000000171. |
| 21524838 | Background | King SE, Gabbott DA. Maternal cardiac arrest--rarely occurs, rarely researched. Resuscitation. 2011 Jul;82(7):795-6. doi: 10.1016/j.resuscitation.2011.03.029. Epub 2011 Apr 6. No abstract available. |
| 39546311 | Derived | Shields AD, Vidosh J, Minard C, Thomson B, Annis-Brayne K, Murphy M, Kavanagh L, Roth CK, Lutgendorf MA, Birsner ML, Rahm SJ, Becker LR, Mosesso V, Schaeffer B, Streitz M, Bhalala U, Gresens A, Phelps J, Sutton B, Wagner R, Melvin LM, Zacherl K, Karwoski L, Behme J, Hoeger A, Nielsen PE. Obstetric Life Support Education for Maternal Cardiac Arrest: A Randomized Clinical Trial. JAMA Netw Open. 2024 Nov 4;7(11):e2445295. doi: 10.1001/jamanetworkopen.2024.45295. |
| Related Info | View source |
| Related Info | View source |
| Reset | Sep 22, 2025 |
| Release | Apr 14, 2026 |
| Reset | May 5, 2026 |
Not provided
| Release Date | Unrelease Date | Unrelease Date Unknown | Reset Date | MCP Release Number |
|---|---|---|---|---|
| Mar 13, 2024 | Aug 16, 2024 | |||
| Sep 1, 2025 | Sep 22, 2025 | |||
| Apr 14, 2026 | May 5, 2026 |
| ID | Term |
|---|---|
| D006323 | Heart Arrest |
| ID | Term |
|---|---|
| D006331 | Heart Diseases |
| D002318 | Cardiovascular Diseases |
Not provided
Not provided