This study evaluates plaque burden and characteristics in early-treated FH patients compared to late-treated FH patients and healthy individuals.

Inclusion Criteria:

• Diagnosed with heterozygous familial hypercholesterolemia or non FH-control
• Adult patients between 25 and 55 years old.

Exclusion Criteria:

• Renal insufficiency, defined as eGFR < 30 ml/min
• Atrial fibrillation
• Any other treatment or clinically relevant condition that could interfere with the conduct or interpretation of the study in the opinion of the investigator
• Inability or unwillingness to comply with the protocol requirements, or deemed by investigator to be unfit for the study.