The Attenuating Effect of Soluble Fiber Consumption on Postprandial Glycemia in Humans

The Attenuating Effect of Soluble Fiber Consumption on Postprandial Glycemia in Humans

The main objective of the current study is to investigate whether consumption of soluble fibers (isomaltodextrin [IMD], partially digestible maltodextrin) and RS4 starch will lower postprandial glycemia as well as postprandial insulin in human subjects with relatively high fasting blood glucose, when consumed with a specific amount of digestible carbohydrate (rice porridge). The primary outcome of the study is the effect of fibers on postprandial blood glucose, whereas the secondary outcome will be its effect on postprandial blood insulin.

Inclusion Criteria:

• Body mass index (18.5 kg/m² ≤ BMI ≤ 29.9 kg/m²)
• No history of abnormal glucose metabolism
• No ongoing use of drugs affecting blood glucose levels
• Fasting blood glucose between 90-110 mg/dL
• Low dietary fiber intake (less than 15 g per day)

Exclusion Criteria:

• Diabetic individuals
• Individuals with history of gastrointestinal disease
• Pregnant or nursing women