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The purpose of this study is to assess the safety and efficacy of Garlic extracts for improving of blood flow velocity in the carotid artery.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Garlic extracts | Experimental | Take 450mg of Garlic extracts(Food Item Making Report Product Name: Vegetable Extract Powder No. 1905, Item Report No.: 202004980275) |
|
| placebo | Placebo Comparator | As a food ingredient that does not affect blood pressure and is harmless to the human body, it is made almost identical in weight and appearance to garlic extract. |
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Garlic extracts | Dietary Supplement | One intake in total |
| |
| Measure | Description | Time Frame |
|---|---|---|
| Change of peak systolic blood flow velocity in the common carotid arteries | Doppler ultrasonography is used for measurement. | Change of peak systolic blood flow velocity before and after 60 minutes garlic extract intake basis in the experimental group |
| Change of end-diastolic blood flow velocity in the common carotid arteries | Doppler ultrasonography is used for measurement. | Change of end-diastolic blood flow velocity before and after 60 minutes garlic extract intake basis in the experimental group |
| Change of diastolic and systolic blood pressure | The blood pressure device is measured by IntelliVue MP50® from Philips. When measuring blood pressure, the study subjects should sit comfortably for at least 5 minutes and then take the measurements. The unit is mmHg and is expressed as an integer. | Change of diastolic and systolic blood pressure before and after 60 minutes garlic extract intake basis in the experimental group |
| Change of peak systolic blood flow velocity in the internal carotid arteries | Doppler ultrasonography is used for measurement. | Change of peak systolic blood flow velocity before and after 60 minutes garlic extract intake basis in the experimental group |
| Change of end-diastolic blood flow velocity in the internal carotid arteries | Doppler ultrasonography is used for measurement. | Change of end-diastolic blood flow velocity before and after 60 minutes garlic extract intake basis in the experimental group |
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Inclusion Criteria:
Exclusion Criteria:
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Pusan national university Yangsan Hospital | Gyeongsang | Yangsan | 50610 | South Korea |
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| Placebo |
| Dietary Supplement |
One intake in total |
|