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The ventilator modality of automatic tube compensation (ATC) can provide variable pressure supports during the weaning process to overcome any change in the resistance of the breathing circuit, endotracheal tube, and airways. The aim of the study is to evaluate the automatic tube compensation (ATC) as a tool for ventilatory weaning in pediatrics after surgeries for congenital cardiac anomalies.
The ventilator modality of automatic tube compensation (ATC) can provide variable pressure supports during the weaning process to overcome any change in the resistance of the breathing circuit, endotracheal tube, and airways. ATC is effective in overcoming the work of breathing caused by airway resistance to allow successful weaning process and extubation. Pressure support ventilation (PSV) has been widely used in the performance of a spontaneous breathing trial because it can compensate to some extent for the additional work of breathing imposed by the endotracheal tube and the breathing circuit. However, it is difficult to recognise the exact pressure support to overcome the tubing resistance during the weaning process till extubation. The aim of the study is to evaluate the automatic tube compensation (ATC) as a tool for ventilatory weaning in pediatrics after surgeries for congenital cardiac anomalies. The primary objective of our study is to compare the efficacy of ATC versus PS as a modality for ventilatory weaning of pediatric postcardiac surgery as regards effects on work of breathing, lung compliance, and alveolar recruitment. The secondary objective is to determine perioperative predictors of extubation failure (requirement for reintubation and mechanical ventilation after prior successful weaning from ventilation, within 48 hours after extubation) after cardiac surgery. Patients will be included after fulfilling weaning criteria and being pain free. a weaning trial for 30 minutes will be commenced according to the following and assessed by the attending physician:- Group A: Weaning trial will be done for 17 patients using PSV 0 cmH2O with 100% automatic tube compensation (ATC).
Group P: Weaning trial will be done for 17 patients using PSV 8 cmH2O without ATC.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Group A | Active Comparator | Weaning trial will be done for 17 patients using PSV 0 cmH2O with 100% automatic tube compensation (ATC). |
|
| Group B | Active Comparator | Weaning trial will be done for 17 patients using PSV 8 cmH2O without ATC. |
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Weaning from mechanical ventilation | Other | Weaning from mechanical ventilation post congenital cardiac surgery |
|
| Measure | Description | Time Frame |
|---|---|---|
| Minute ventilation | Tidal volume (ml/kg) × respiratory rate (breath / minutes) | 1 year |
| Oxygenation index (OI) | mean air way pressure × FIO2/PaO2 | 1 year |
| Work of breathing (WOB) | (∆ V × flow × R + Volume/compliance) (J/L/Kg) | 1 year |
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Inclusion Criteria:
Exclusion Criteria:
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Alexandria university | Alexandria | 23541 | Egypt |
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| ID | Term |
|---|---|
| D006330 | Heart Defects, Congenital |
| ID | Term |
|---|---|
| D018376 | Cardiovascular Abnormalities |
| D002318 | Cardiovascular Diseases |
| D006331 | Heart Diseases |
| D000013 | Congenital Abnormalities |
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| D009358 | Congenital, Hereditary, and Neonatal Diseases and Abnormalities |