Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
In recent years, due to the improvement in the survival rate of the intensive care unit, the problem of severe systemic fatigue (Intensive care unit acquired weakness; ICUAW) has continued to receive attention. Muscle mass decreases by 3-11% within a week, resulting in decreased muscle strength and muscle atrophy. Current studies suggest that ICUAW can lead to poorer function, prolonged ICU stay, and decreased quality of life.
This study aimed to understand the muscle strength of critically ill patients and to explore the effect of exercise intervention on improving muscle strength. The experimental group received a four-week exercise bike intervention plus conventional rehabilitation exercises, while the control group received conventional rehabilitation exercises.
The content of the exercise is to use an exercise bike, start pedaling on the first day, time setting: 20 minutes, speed: 2, and adopt passive mode. If you can complete the exercise on the first day, the time will be adjusted to 30 minutes on the second day. If you cannot complete the exercise on the first day, the time will still start from 20 minutes on the second day. The maximum time is 30 minutes. If you can complete 30 minutes of passive exercise for 3 consecutive days, the fourth day will be adjusted to active exercise. The entire exercise training is seven days a week, once a day, once a 30-minute, at least 5 days. Those who were discharged to the general ward continued to complete this exercise training for up to 28 days. Stop exercising if heartbeat > 140, mean arterial pressure < 65, blood oxygen < 90%, respiration > 35 beats/min, or the patient requests to stop during exercise.
Not provided
Not provided
Not provided
Not provided
| Label | Type | Description | Intervention Names |
|---|---|---|---|
| exercise bike | Experimental | exercise is to use an exercise bike, start pedaling on the first day, time setting: 20 minutes, speed: 2, and adopt passive mode. If you can complete the exercise on the first day, the time will be adjusted to 30 minutes on the second day. If you cannot complete the exercise on the first day, the time will still start from 20 minutes on the second day. The maximum time is 30 minutes. If you can complete 30 minutes of passive exercise for 3 consecutive days, the fourth day will be adjusted to active exercise. The entire exercise training is seven days a week, once a day, once a 30-minute, at least 5 days. Those who were discharged to the general ward continued to complete this exercise training for up to 28 days. |
|
| regular rehabilitation exercises | No Intervention | walking exercise |
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| exercise bike | Other | exercise is to use an exercise bike, start pedaling on the first day, time setting: 20 minutes, speed: 2, and adopt passive mode. If you can complete the exercise on the first day, the time will be adjusted to 30 minutes on the second day. If you cannot complete the exercise on the first day, the time will still start from 20 minutes on the second day. The maximum time is 30 minutes. If you can complete 30 minutes of passive exercise for 3 consecutive days, the fourth day will be adjusted to active exercise. The entire exercise training is seven days a week, once a day, once a 30-minute, at least 5 days. Those who were discharged to the general ward continued to complete this exercise training for up to 28 days. |
| Measure | Description | Time Frame |
|---|---|---|
| Basic Demographic Health Assessment Form | Age, sex, diagnosis, disease severity, reason for ICU admission | baseline |
| days in intensive care unit | Health Assessment Form | baseline |
| days on ventilator | Health Assessment Form | baseline |
| total days in hospital | Health Assessment Form | baseline |
| body mass index | Health Assessment Form | baseline |
| level of albumin | Health Assessment Form | baseline |
| The daily observation record sheet includes | Vital signs,respirator is used or not,bicycle use pattern,speed and time,reasons for stopping | up to 28 days |
| Measure | Description | Time Frame |
|---|---|---|
| Hand grip strength | Using a Grip Strength Tester to Measure Dominant Hand Muscle Strength | baseline(T0) |
| Hand grip strength | Using a Grip Strength Tester to Measure Dominant Hand Muscle Strength |
Not provided
Inclusion Criteria:
Exclusion Criteria:
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
| Name | Affiliation | Role |
|---|---|---|
| Tao-Fen Hsiung | Taipei Veterans General Hospital, Taiwan | Study Director |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| TaipeiVGH | Taipei | Taipei City, Taiwan | Taiwan |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 18511703 | Result | Ali NA, O'Brien JM Jr, Hoffmann SP, Phillips G, Garland A, Finley JC, Almoosa K, Hejal R, Wolf KM, Lemeshow S, Connors AF Jr, Marsh CB; Midwest Critical Care Consortium. Acquired weakness, handgrip strength, and mortality in critically ill patients. Am J Respir Crit Care Med. 2008 Aug 1;178(3):261-8. doi: 10.1164/rccm.200712-1829OC. Epub 2008 May 29. | |
| 24040200 |
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
|
| 3 days after intervention(T1) |
| Hand grip strength | Using a Grip Strength Tester to Measure Dominant Hand Muscle Strength | 7 days after intervention(T2) |
| Hand grip strength | Using a Grip Strength Tester to Measure Dominant Hand Muscle Strength | 10 days after intervention(T3) |
| Hand grip strength | Using a Grip Strength Tester to Measure Dominant Hand Muscle Strength | 14 days after intervention(T4) |
| Hand grip strength | Using a Grip Strength Tester to Measure Dominant Hand Muscle Strength | 17 days after intervention(T5) |
| Hand grip strength | Using a Grip Strength Tester to Measure Dominant Hand Muscle Strength | 21 days after intervention(T6) |
| Hand grip strength | Using a Grip Strength Tester to Measure Dominant Hand Muscle Strength | 28 days after intervention(T7) |
| foot lift | Use a tape to measure foot lift | baseline(T0) |
| foot lift | Use a tape to measure foot lift | 3 days after intervention(T1) |
| foot lift | Use a tape to measure foot lift | 7days after intervention(T2) |
| foot lift | Use a tape to measure foot lift | 10days after intervention(T3) |
| foot lift | Use a tape to measure foot lift | 14days after intervention(T4) |
| foot lift | Use a tape to measure foot lift | 17ays after intervention(T5) |
| foot lift | Use a tape to measure foot lift | 21days after intervention(T6) |
| foot lift | Use a tape to measure foot lift | 28days after intervention(T7) |
| walking distance in 6 minutes | Measure 6-minute walking distance | baseline(T0) |
| walking distance in 6 minutes | Measure 6-minute walking distance | 3 days after intervention(T1) |
| walking distance in 6 minutes | Measure 6-minute walking distance | 7 days after intervention(T2) |
| walking distance in 6 minutes | Measure 6-minute walking distance | 10days after intervention(T3) |
| walking distance in 6 minutes | Measure 6-minute walking distance | 14days after intervention(T4) |
| walking distance in 6 minutes | Measure 6-minute walking distance | 17days after intervention(T5) |
| walking distance in 6 minutes | Measure 6-minute walking distance | 21days after intervention(T6) |
| walking distance in 6 minutes | Measure 6-minute walking distance | 28ays after intervention(T7) |
| Camargo Pires-Neto R, Fogaca Kawaguchi YM, Sayuri Hirota A, Fu C, Tanaka C, Caruso P, Park M, Ribeiro Carvalho CR. Very early passive cycling exercise in mechanically ventilated critically ill patients: physiological and safety aspects--a case series. PLoS One. 2013 Sep 9;8(9):e74182. doi: 10.1371/journal.pone.0074182. eCollection 2013. |
| 12472328 | Result | De Jonghe B, Sharshar T, Lefaucheur JP, Authier FJ, Durand-Zaleski I, Boussarsar M, Cerf C, Renaud E, Mesrati F, Carlet J, Raphael JC, Outin H, Bastuji-Garin S; Groupe de Reflexion et d'Etude des Neuromyopathies en Reanimation. Paresis acquired in the intensive care unit: a prospective multicenter study. JAMA. 2002 Dec 11;288(22):2859-67. doi: 10.1001/jama.288.22.2859. |
| 30427933 | Result | Eggmann S, Verra ML, Luder G, Takala J, Jakob SM. Effects of early, combined endurance and resistance training in mechanically ventilated, critically ill patients: A randomised controlled trial. PLoS One. 2018 Nov 14;13(11):e0207428. doi: 10.1371/journal.pone.0207428. eCollection 2018. |
| 24825371 | Result | Hermans G, Van Mechelen H, Clerckx B, Vanhullebusch T, Mesotten D, Wilmer A, Casaer MP, Meersseman P, Debaveye Y, Van Cromphaut S, Wouters PJ, Gosselink R, Van den Berghe G. Acute outcomes and 1-year mortality of intensive care unit-acquired weakness. A cohort study and propensity-matched analysis. Am J Respir Crit Care Med. 2014 Aug 15;190(4):410-20. doi: 10.1164/rccm.201312-2257OC. |
| 28030555 | Result | Kho ME, Molloy AJ, Clarke FJ, Ajami D, McCaughan M, Obrovac K, Murphy C, Camposilvan L, Herridge MS, Koo KK, Rudkowski J, Seely AJ, Zanni JM, Mourtzakis M, Piraino T, Cook DJ; Canadian Critical Care Trials Group. TryCYCLE: A Prospective Study of the Safety and Feasibility of Early In-Bed Cycling in Mechanically Ventilated Patients. PLoS One. 2016 Dec 28;11(12):e0167561. doi: 10.1371/journal.pone.0167561. eCollection 2016. |
| 30956804 | Result | Kho ME, Molloy AJ, Clarke FJ, Reid JC, Herridge MS, Karachi T, Rochwerg B, Fox-Robichaud AE, Seely AJ, Mathur S, Lo V, Burns KE, Ball IM, Pellizzari JR, Tarride JE, Rudkowski JC, Koo K, Heels-Ansdell D, Cook DJ. Multicentre pilot randomised clinical trial of early in-bed cycle ergometry with ventilated patients. BMJ Open Respir Res. 2019 Feb 18;6(1):e000383. doi: 10.1136/bmjresp-2018-000383. eCollection 2019. |
| 28538781 | Result | Machado ADS, Pires-Neto RC, Carvalho MTX, Soares JC, Cardoso DM, Albuquerque IM. Effects that passive cycling exercise have on muscle strength, duration of mechanical ventilation, and length of hospital stay in critically ill patients: a randomized clinical trial. J Bras Pneumol. 2017 Mar-Apr;43(2):134-139. doi: 10.1590/S1806-37562016000000170. |