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Slow deep breathing actives the vagal nerve and leads to a natural reduction in physiological parameters such as blood pressure, heart rate and digestion. The effects of these techniques have not been assessed in pregnancy. The primary objective is to assess the effects of various yogic deep breathing techniques on blood pressure during pregnancy. The breathing exercises will include Alternate nostril breathing, Bhramari breathing, and Sheetali breathing. A secondary objective will be to assess the effects of these breathing exercises on other physiological parameters including heart rate, heart rate variability, body temperature, cardiac output, vascular resistance and respiratory rate.
The trial will be conducted as a pilot study in one study visit, which will be conducted in two phases. Phase I will be conducted on normotensive pregnant women and Phase II will be conducted on hypertensive pregnant women. Participants will be in their third trimester of pregnancy (28 weeks onwards).
Upon presentation, they will be randomized into one of three groups: Alternate nostril breathing, Bhramari breathing or Sheetali breathing. Maternal monitoring devices will be placed on the patient before the intervention. The fetus will be monitored by external monitors consisting of a fetal heart rate monitor and tocodynamometer to assess uterine activity. Fetal position will be assessed before and after the intervention by ultrasound. All devices will obtain a reading for 15 minutes before, during and after the intervention.
Intervention: In an upright, seated position, the participant will engage in a total of 15 minutes of one deep breathing technique. The breathing practice will be conducted in three, 5-minute increments with a one-minute break between each session. These breathing techniques are easy to learn and participants will be taught how to perform the exercise (visual demonstration, verbal and written instructions will be provided). Participants will be given the opportunity to practice the breathing technique and ask any questions prior to initiating monitoring.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Alternate Nostril Breathing Phase I | Active Comparator | Alternate nostril breathing for normotensive women in 3rd trimester of pregnancy |
|
| Bhramari Breathing Phase I | Active Comparator | Bhramari breathing for normotensive women in 3rd trimester of pregnancy |
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| Sheetali Breathing Phase I | Active Comparator | Sheetali breathing for normotensive women in 3rd trimester of pregnancy |
|
| Alternate Nostril Breathing Phase II | Active Comparator | Alternate nostril breathing for hypertensive women in 3rd trimester of pregnancy |
|
| Bhramari Breathing Phase II | Active Comparator | Bhramari breathing for hypertensive women in 3rd trimester of pregnancy |
|
| Sheetali Breathing Phase II |
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Alternate Nostril Breathing | Behavioral | Utilizing Pranayama (deep breathing technique) in normotensive and hypertensive women in 3rd trimester of pregnancy |
|
| Measure | Description | Time Frame |
|---|---|---|
| Change of blood pressure from baseline in normotensive and hypertensive women in 3rd trimester pregnancy while utilizing various pranayama breathing techniques | Continuous blood pressure monitored while participants engage in a deep breathing technique (pranayama breathing) | One visit, 15 minute intervention |
| Measure | Description | Time Frame |
|---|---|---|
| Change of heart rate from baseline to after the intervention | Continuous heart rate monitor will be applied | One visit, 15 minute intervention |
| Change in body temperature from baseline to after the intervention |
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Inclusion Criteria:
- Any pregnant woman in the 3rd trimester after 28 weeks of pregnancy who is/has
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Shilpa Babbar, MD | Children's Mercy Hospital Kansas City | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Advent Health Shawnee Mission Birth Center | Merriam | Kansas | 66204 | United States |
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| ID | Term |
|---|---|
| D046110 | Hypertension, Pregnancy-Induced |
| ID | Term |
|---|---|
| D011248 | Pregnancy Complications |
| D005261 | Female Urogenital Diseases and Pregnancy Complications |
| D000091642 | Urogenital Diseases |
| D006973 | Hypertension |
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Pilot, randomized, controlled trial
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Sheetali breathing for hypertensive women in 3rd trimester of pregnancy |
|
| Bhramari Breathing | Behavioral | Utilizing Pranayama (deep breathing technique) in normotensive and hypertensive women in 3rd trimester of pregnancy |
|
| Sheetali Breathing | Behavioral | Utilizing Pranayama (deep breathing technique) in normotensive and hypertensive women in 3rd trimester of pregnancy |
|
Continuous temperature monitor will be applied
| One visit, 15 minute intervention |
| Change in cardiac output from baseline to after the intervention | Continuous cardiac output monitor will be applied | One visit, 15 minute intervention |
| D014652 | Vascular Diseases |
| D002318 | Cardiovascular Diseases |