The aim of this study is to (a) investigate the effects of manual lymphatic drainage and transcutaneous electrical nerve stimulation on the severity of syndrome symptoms, pain, heart rate variability, and quality of life in women with premenstrual syndrome, and (b) compare the effectiveness of these two methods. Female participants who met the inclusion criteria and volunteered to participate in the study will be called approximately one week before menstruation. After the participants are randomly divided into 3 groups, their baseline assessments will be made. Then, the participants will be treated according to the group they are assigned to. Treatments will be applied for 5 days and once a day. No treatment will be applied to the control group. The assessments will be repeated after the treatment, on 1st day of menstruation, two days before the next menstruation, and on the first day of the next menstruation. The hypothesis of this study is that manual lymphatic drainage and transcutaneous electrical nerve stimulation have positive effects on the severity of premenstrual syndrome symptoms, pain, heart rate variability, and quality of life.

Inclusion Criteria:

• women aged between18-45 years-old
• regular menstrual cycles (cycles of 21-35 days with a bleeding time of 3-10 days)
• premenstrual syndrome (according to the premenstrual syndrome scale, be above 110 points)

Exclusion Criteria:

• pregnancy
• premenstrual dysphoric disorder
• menopause
• chronic disease
• continuous use of medication
• under hormonal therapy
• infection
• using any method to cope with premenstrual syndrome

The researcher who made the assessments and participants do not know which group participants belong to.