The purpose of this study is to determine the effect of Octreotide on saliva enzymes. The study team hypothesizes that Octreotide will decrease the levels of certain proteins, specifically the metalloproteinase family.

This is a healthy volunteer pilot study. The purpose of this study is to determine the effect of a drug, Octreotide, on saliva enzymes in order to see if this drug can help prevent pharyngo-cutaneous fistulas (an abnormal tissue connection in the pharynx) in patients undergoing laryngectomy.

Inclusion Criteria:

• Healthy adults between the ages of 18-40 years old
• Healthy volunteer who is willing to undergo research activities
• Healthy volunteer with no self-report of disease, oral symptoms or lesions, or cold or flu like symptoms that would affect the reflective measurements in the oral cavity
• Ability to understand and the willingness to sign a written informed consent document

Exclusion Criteria:

• Pregnant or nursing women
• Children under the age of 18 or adults over 40
• Complaint of oral symptoms (self-reported)
• Medical condition affecting saliva (e.g. Sjogren's)
• History of head/neck radiation
• Medication that might affect saliva (e.g. Proton Pump Inhibitors)
• Known allergy to Octreotide
• Non-English speaking
• Diabetes, gallbladder disease, heart disease, high blood pressure, a heart rhythm disorder, thyroid problems, pancreatitis, kidney disease, or liver disease (self-reported)