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Knee osteoarthritis is one of the most common causes of pain and loss of function in the elderly population and is a source of socioeconomic costs. Selective denervation of the superior medial, superior lateral and inferior medial genicular nerves, which provide the sensory innervation of the knee joint, is an effective treatment method used to relieve pain and improve functional capacity. Radiofrequency neurolysis of genicular nerves (RFN) is accepted as an effective technique for the treatment of knee pain. However, due to higher equipment costs, longer procedure times, and procedure-related pain, alternative treatments are needed.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Radiofrequency Neurolysis | Active Comparator | Radiofrequency Neurolysis of genicular nerves |
|
| Chemical Neurolysis | Experimental | Chemical Neurolysis of genicular nerves |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Genicular nerve radiofrequency neurolysis | Procedure | Neurolysis of superomedial, superolateral and inferomedial genicular nerves |
|
| Measure | Description | Time Frame |
|---|---|---|
| Numerical Rating Scale (NRS) | Pain Score Change The 11-point NRS consists of numbers between 0 and 10 where 0 indicates "no pain" and 10 indicates "maximum pain." The patient is instructed to identify one number between 0 and 10, which is best representative of their pain intensity. | Change from baseline to 6 months after procedure |
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Inclusion Criteria:
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Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| selin guven kose | Diskapi Yildirim Beyazit Education and Research Hospital | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Diskapi Yildirim Beyazit Training and Research Hospital | Ankara | 06110 | Turkey (Türkiye) |
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| ID | Term |
|---|---|
| D020370 | Osteoarthritis, Knee |
| ID | Term |
|---|---|
| D010003 | Osteoarthritis |
| D001168 | Arthritis |
| D007592 | Joint Diseases |
| D009140 | Musculoskeletal Diseases |
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| Genicular nerve chemical neurolysis | Procedure | Neurolysis of superomedial, superolateral and inferomedial genicular nerves |
|
| D012216 |
| Rheumatic Diseases |