Administration of Human Chorionic Gonadotrophin Before Secretory Transformation of Frozen-thawed Embryo Transfer Cycles

Administration of Human Chorionic Gonadotrophin Before Secretory Transformation of Frozen-thawed Embryo Transfer Cycles

Successful embryo implantation is complicated process that requires synchrony between good-quality embryos and receptive endometrium. Human chorionic gonadotropin (hCG), is one of the initial embryonic signals and the major embryoendometrial relationship regulator. This study will be conducted to to investigate the role of parenteral hCG used for the transfer of cryopreserved- thawed embryos with HRT cycles in the outcome of artificially prepared frozen embryo transfer (FET) cycles.

Inclusion Criteria:

• Patient age ≤ 38 years.
• Normal 3D transvaginal ultrasound.
• At least two good quality embryos cryopreserved by vitrification.
• No GnRH agonists administration before FET cycle.

Exclusion Criteria

• Endometriosis.
• Uterine anomalies.
• Evidence of hydrosalpinx by hystrosalpingography or ultrasound.
• Evidence of immune disease, hematological or hormonal disorder.