Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
| Name | Class |
|---|---|
| University Düsseldorf | OTHER |
Not provided
Not provided
Not provided
Not provided
A cardiac arrest event has severe impact on the patient´s health-related quality of life. Survival of cardiac arrest does not innately translate to favorable quality of life. In particular, highly invasive resuscitation strategies, including extracorporeal cardio-pulmonary resuscitation (ECPR) due to therapy-refractory cardiac arrest, may have impact on long-term outcomes. Therefore, apart from acute medical treatment and physical rehabilitation, long-term effects on cardio-pulmonary, physical and neuro-psychiatric functions after cardiac arrest survival have to be evaluated and optimized. We plan to investigate a bundle of cardio-pulmonary, physical and neuro-psychiatric functions in patients who survived a therapy-refratory cardiac arrest with ECPR.
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
| Label | Type | Description | Intervention Names |
|---|---|---|---|
| ECPR survivor | Adult patient who survived therapy-refractory cardiac arrest with extracorporeal cardiopulmonary resuscitation (ECPR). |
Not provided
| Measure | Description | Time Frame |
|---|---|---|
| Left ventricular ejection fraction (LVEF) | LVEF measured with transthoracic echocardiography. | LVEF witihin one year after index cardiac arrest event. |
| Measure | Description | Time Frame |
|---|---|---|
| Cognitive function | Cognitive function measured with a standardized questionnaire and following established scores:
| Cognitive function witihin one year after index cardiac arrest event. |
Not provided
Inclusion Criteria:
Exclusion Criteria:
Not provided
Not provided
Not provided
Adult patients who suffered from cardiac arrest and were treated with ECPR.
| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Tharusan Thevathasan, MD | Contact | +49 30 450 613 687 | tharusan.thevathasan@charite.de | |
| Carsten Skurk, MD | Contact | +49 30 450 513 725 | carsten.skurk@charite.de |
| Name | Affiliation | Role |
|---|---|---|
| Carsten Skurk, MD | Charite Univesity | Study Director |
| Tharusan Thevathasan, MD | Charite Univesity | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Charité - Universitätsmedizin Berlin | Berlin | 12203 | Germany |
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
| ID | Term |
|---|---|
| D006323 | Heart Arrest |
| D009203 | Myocardial Infarction |
| D012770 | Shock, Cardiogenic |
| ID | Term |
|---|---|
| D006331 | Heart Diseases |
| D002318 | Cardiovascular Diseases |
| D017202 | Myocardial Ischemia |
| D014652 | Vascular Diseases |
Not provided
Not provided
Not provided
Not provided
Not provided
Blood draw: Sodium, Potassium, Chloride, Calcium, Magnesium, Creatinine, Urea, Uric acid, Bilirubin, Cholesterol (total, HDL, LDL), Triglyceride, Lipoprotein (a), HbA1c, NT-proBNP, Creatinkinase (CK), CK-MB, Myoglobin, ALT, AST, Gamma-GT, Alkaline phosphatase, GLDH, Lipase, LDH, CRP, Procalcitonin, Albumin, Iron, Ferritin, Transferrin, Transferrin saturation, Haptoglobin, Free hemoglobin, Complete blood count, Quick, PTT, TSH, T4, T3, Cortisol, venous arterial blood gas.
| Sign and symptoms of heart failure | Sign and symptoms of heart failure measured with a standardized questionnaire and following established score: European Quality of Life 5 Dimensions 3 Level Version [0-100 points; higher score means better outcome]. | Sign and symptoms of heart failure witihin one year after index cardiac arrest event. |
| Activity of daily living (ADL) | ADL measured with a standardized questionnaire and following estbalished score: Barthel index [0-100 points; higher score means better outcome]. | ADL witihin one year after index cardiac arrest event. |
| Comorbidity level | Comorbidity level measured with following established score: Charlson comorbidity index [0-24 points; lower score means better outcome]. | Comorbidity level witihin one year after index cardiac arrest event. |
| Number of cardiovascular medications | Number of cardiovascular medications documented with a standardized questionnaire. | Number of cardiovascular medication witihin one year after index cardiac arrest event. |
| Cardiac stress test: Ergometry | Quantitative test to evaluate cardiopulmonary exercise tolerance and physical capacity by using a bicycle. | Physical function witihin one year after index cardiac arrest event. |
| Cardiac stress test: Walking distance | Quantitative test to evaluate endurance and aerobic capacity by walking for six minutes (six minute walk test). | Physical function witihin one year after index cardiac arrest event. |
| Vital function: Blood pressure | Non-invasive blood pressure measurement at rest (unit: mmHg). | Blood pressure witihin one year after index cardiac arrest event. |
| Vital function: Electrocardiogram (ECG) | 12-lead ECG measurement at rest. | ECG activity witihin one year after index cardiac arrest event. |
| Vital function: Peripheral oxygen saturation | Peripheral oxygen saturation measurement at rest by using pulsoximetry (unit: percent). | Peripheral oxygen saturation witihin one year after index cardiac arrest event. |
| D007238 |
| Infarction |
| D007511 | Ischemia |
| D010335 | Pathologic Processes |
| D013568 | Pathological Conditions, Signs and Symptoms |
| D009336 | Necrosis |
| D012769 | Shock |