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Principal Investigator left the institution
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Previous studies have shown that cardiorespiratory fitness (how well the heart and lungs are able to function during physical activity) is often reduced in people with psychosis. The goal of this research study is to test the hypothesis that aerobic exercise can lead to small changes in brain functioning that can influence visual perception and attention in psychosis. The type of aerobic exercise used in this study is called Sprint Interval Training, or "SIT". Information from this study will help to develop interventions that enhance cognition and maximize the quality of life for persons living with psychosis.
The exercise procedure used is called SIT, which involves training rigorously on a stationary bike for a short period of time followed by a resting period.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Sprint Interval Training (SIT) | The 1-session SIT protocol will include "Work" bouts performed at maximal intensity targets. Three "Work" bouts will be performed at 20-second intervals separated by 2 recovery bouts consisting of 2 minutes of low-intensity cycling. The SIT session will employ a standardized warm up and cool down of 3 minutes at a self-selected light intensity, per current guidelines. SIT sessions will take 15 minutes to complete. |
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| Stretching | Stretching will include a low-intensity range of motion and stretching exercises with session duration (15 minutes) being matched to SIT. |
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Sprint Interval Training (SIT) | Other | Active arm-- exercise dictated by protocol |
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| Measure | Description | Time Frame |
|---|---|---|
| Change in Individual Alpha Frequency | A prominent neural oscillatory rhythm measured from resting EEG. | through study completion, on average 2 weeks |
| Change in Visual Attention | Computerized tasks that measure speeded sustained attention. | through study completion, on average 2 weeks |
| Change in Visual Perception | Computerized tasks that measure speeded visual perception | through study completion, on average 2 weeks |
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Inclusion Criteria:
Exclusion Criteria:
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Individuals in good health with a psychotic disorder.
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| Name | Affiliation | Role |
|---|---|---|
| Ian Ramsay | University of Minnesota | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| University of Minnesota | Minneapolis | Minnesota | 55455 | United States |
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| ID | Term |
|---|---|
| D011618 | Psychotic Disorders |
| D012559 | Schizophrenia |
| D009043 | Motor Activity |
| ID | Term |
|---|---|
| D019967 | Schizophrenia Spectrum and Other Psychotic Disorders |
| D001523 | Mental Disorders |
| D001519 | Behavior |
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| ID | Term |
|---|---|
| D000072696 | High-Intensity Interval Training |
| ID | Term |
|---|---|
| D064797 | Physical Conditioning, Human |
| D015444 | Exercise |
| D009043 | Motor Activity |
| D009068 | Movement |
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| D009142 |
| Musculoskeletal Physiological Phenomena |
| D055687 | Musculoskeletal and Neural Physiological Phenomena |