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Collect 120 women(A. Overactive bladder、B. Stress incontinence、C. Interstitial cystitis D. Female sexual dysfunction), Low Energy Extracorporeal Shock Wave (LiESWT) therapy once a week, duration 8 weeks(B.、C. PRP treatment at 1, 5, 9 weeks), and to complete all treatment after 4 weeks and 24 weeks back to the clinic, evaluation questionnaire (OABSS、UDI-6、IIQ-7、ICIQ-SF、POPDI-6、FSFI)、Urinary tract dynamics test、Urination log、Cotton pad test、Blood test(ESR、CA125、CBC、CRP). ○DLow Energy Extracorporeal Shock Wave (LiESWT) therapy once a week, duration 4 weeks, and to complete all treatment 4th and after 4 weeks back to the clinic, Pelvic Doppler ultrasound ,evaluation questionnaire (OABSS、UDI-6、IIQ-7、ICIQ-SF、POPDI-6、FSFI).
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| A. Overactive bladder | Experimental | Overactive bladder (LiESWT therapy once a week, duration 8 weeks) |
|
| B. Stress incontinence | Experimental | Stress incontinence (LiESWT therapy once a week, duration 8 weeks + PRP therapy once a month, duration 3 months) |
|
| C. Interstitial cystitis | Experimental | Interstitial cystitis (LiESWT therapy once a week, duration 8 weeks + PRP therapy once a month, duration 3 months) |
|
| D. Female sexual dysfunction | Experimental | Female sexual dysfunction (LiESWT therapy once a week, duration 8 weeks) |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| "Storz Medical" Extracoporeeal Shock Wave Therapy System | Device | A. B. C. D. groups need to Low Energy Extracorporeal Shock Wave (LiESWT) therapy once a week, duration 8 weeks(B.、C. groups needs to be combined PRP treatment at 1, 5, 9 weeks) |
| Measure | Description | Time Frame |
|---|---|---|
| Reduce bladder leakage and symptoms of overactive bladder, including urgency, incontinence and nocturia. | 1.Questionnaire assessment before and after treatment (OABSS, UDI-6, IIQ-7, ICIQ-SF, POPDI-6, FSFI) . 2.urodynamic examination before and after treatment | 8 months |
| Assess the patient for changes in lower abdominal pain | VAS pain index record before and after treatment | 8 months |
| Measure | Description | Time Frame |
|---|---|---|
| Promote the repair and proliferation of blood vessels in the vulva to improve sexual function and improve the overall quality of sexual life. | Doppler ultrasound of the vulva to record the degree of blood congestion before and after treatment | 2 months |
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Inclusion Criteria:
One of the following symptoms can be included:
The blood test confirmed that the number of platelets was 150,000 to 450,000 / UL, and the coagulation function (PT) index was normal.
Women over 20 years.
Exclusion Criteria:
women with pelvic floor dysfunction
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| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Cheng-Yu Long, Professor | Contact | +886-7-3121101 | 6428 | urolong@yahoo.com.tw |
| Kun-Ling Lin, Asst. Prof. | Contact | +886-7-3121101 | 6428 | nancylin95@gmail.com |
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Kaohsiung Medical University Chung-Ho Memorial Hospital (KMUH) | Recruiting | Kaohsiung City | Sanmin Dist | 80756 | Taiwan |
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Only one arm for each disease (LiESWT group)
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|
| ID | Term |
|---|---|
| D053201 | Urinary Bladder, Overactive |
| D014550 | Urinary Incontinence, Stress |
| D018856 | Cystitis, Interstitial |
| ID | Term |
|---|---|
| D001745 | Urinary Bladder Diseases |
| D014570 | Urologic Diseases |
| D052776 | Female Urogenital Diseases |
| D005261 | Female Urogenital Diseases and Pregnancy Complications |
| D000091642 | Urogenital Diseases |
| D052801 | Male Urogenital Diseases |
| D059411 | Lower Urinary Tract Symptoms |
| D020924 | Urological Manifestations |
| D012816 | Signs and Symptoms |
| D013568 | Pathological Conditions, Signs and Symptoms |
| D014549 | Urinary Incontinence |
| D014555 | Urination Disorders |
| D003556 | Cystitis |
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