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This project will use deep learning to classify colonoscopy images of different severity of ulcerative colitis, so as to assist clinicians in the accurate diagnosis of ulcerative colitis.
In this project, artificial intelligence was used to colonoscopic images of patients with ulcerative colitis with different disease activity levels and classify them according to the evaluation standard Mayo score to assist endoscopists in identifying disease activity levels of patients with ulcerative colitis during colonoscopy. It can help clinical endoscopists to accurately identify, and the visualization technology of artificial intelligence category response map can comprehensively display the areas with high importance for deep network classification results, and visualize the experimental lesion sites, thus effectively verifying the reliability and interpretability of deep network. This study can provide strong support for accurate identification of disease activity in clinical ulcerative colitis, effectively reduce the workload of clinicians, and provide a convenient, effective and practical clinical teaching tool.
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| Measure | Description | Time Frame |
|---|---|---|
| The accuracy of deep learning model in the training and validation datasets assessment of Mayo score in ulcerative colitis patients. | In the training and validation datasets, we plotted the AUC (area under curve) for Mayo 0, Mayo 1, Mayo 2, and Mayo 3 to evaluate our model objectively. | Through study completion, an average of 1 year. |
| Measure | Description | Time Frame |
|---|---|---|
| The accuracy and time efficiency of endoscopists assessment of Mayo score in ulcerative colitis patients. | The dataets were randomly assigned to endoscopists. All endoscopists were trained in diagnostic studies, finished both clinical and specific endoscopic training, and were not involved in the enrollment and labeling of the patients and images. During the comparison test, all data were randomized and deidentified beforehand. The average time spent by 10 endoscopists in diagnosing the test dataset in the deep learning model and the number of correct cases were analyzed. |
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Inclusion Criteria:
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The images were retrieved from the endoscopy database of Army Medical Center of PLA and obtained from the colonoscopy of patients with ulcerative colitis who met the inclusion criteria. The data images were used to establish and verify the model of ai-assisted recognition system.
| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Yanling Wei, professor | Contact | +8615310354666 | lingzi016@tmmu.edu.cn |
| Name | Affiliation | Role |
|---|---|---|
| Yanling Wei, Professor | Third Military Medical University | Study Director |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Third Military Medical University | Chongqing | Chongqing Municipality | 400042 | China |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 37251086 | Derived | Qi J, Ruan G, Ping Y, Xiao Z, Liu K, Cheng Y, Liu R, Zhang B, Zhi M, Chen J, Xiao F, Zhao T, Li J, Zhang Z, Zou Y, Cao Q, Nian Y, Wei Y. Development and validation of a deep learning-based approach to predict the Mayo endoscopic score of ulcerative colitis. Ther Adv Gastroenterol. 2023 May 22;16:17562848231170945. doi: 10.1177/17562848231170945. eCollection 2023. |
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| ID | Term |
|---|---|
| D003093 | Colitis, Ulcerative |
| ID | Term |
|---|---|
| D003092 | Colitis |
| D005759 | Gastroenteritis |
| D005767 | Gastrointestinal Diseases |
| D004066 | Digestive System Diseases |
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| Through study completion, an average of 1 year. |
| D015212 |
| Inflammatory Bowel Diseases |
| D003108 | Colonic Diseases |
| D007410 | Intestinal Diseases |