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| Name | Class |
|---|---|
| Novo Nordisk A/S | INDUSTRY |
| Elsass Foundation | OTHER |
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Currently, there is a paucity of quality research within the field of health science with a focus on persons with intellectual disabilities, and especially how longer lasting periods of varied physical activity affects the target group. There is a lack of insight, in how persons with intellectual disabilities learns and retains movement skills. Thus, the research group behind this project will investigate the following research questions:
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Physical Activity group (PA-group) | Experimental | The intervention group. Participants with intellectual disabilities is recruited from a local daily activity center, where the participants participate in teacher-organized physical activity ~2 hours/day, 5 days/week. |
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| Control Group (CON-group) | No Intervention | The control group. The participants with intellectual disabilities is recruited from daily activity centers, which does not use physical activity in their daily work with the participants. |
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Physical activity | Other | 2 hours of physical activity per day, 5 days per week, for the intervention period |
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| Measure | Description | Time Frame |
|---|---|---|
| Change in body weight | Body weight in kilograms | Measurements will be obtained at pre-intervention, (0 weeks), mid intervention (14 weeks) and post intervention (40 weeks) |
| Change in body fat mass | Body fat mass in kilograms | Measurements will be obtained at pre-intervention, (0 weeks), mid intervention (14 weeks) and post intervention (40 weeks) |
| Change in lean mass | Lean body mass in kilograms | Measurements will be obtained at pre-intervention, (0 weeks), mid intervention (14 weeks) and post intervention (40 weeks) |
| Change in fat free mass | Fat free mass in kilograms | Measurements will be obtained at pre-intervention, (0 weeks), mid intervention (14 weeks) and post intervention (40 weeks) |
| Change in cardiovascular fitness | Change in heart rate during the same absolute submaximal exercise intensity | Measurements will be obtained at pre-intervention, (0 weeks), mid intervention (14 weeks) and post intervention (40 weeks) |
| Change in areal bone mineral density of the whole body | Areal bone mineral density in grams per square centimeter (g/cm2) of the whole body | Measurements will be obtained at pre-intervention, (0 weeks), mid intervention (14 weeks) and post intervention (40 weeks) |
| Change in T-scores of the whole body |
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Inclusion Criteria:
Exclusion Criteria:
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Department of Nutrition, Exercise and Health, University of Copenhagen | Copenhagen | Capital Region of Denmark | 2200 | Denmark |
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| Label | URL |
|---|---|
| Related Info | View source |
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| ID | Term |
|---|---|
| D008607 | Intellectual Disability |
| D009043 | Motor Activity |
| ID | Term |
|---|---|
| D019954 | Neurobehavioral Manifestations |
| D009461 | Neurologic Manifestations |
| D009422 | Nervous System Diseases |
| D012816 | Signs and Symptoms |
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| ID | Term |
|---|---|
| D015444 | Exercise |
| ID | Term |
|---|---|
| D009043 | Motor Activity |
| D009068 | Movement |
| D009142 | Musculoskeletal Physiological Phenomena |
| D055687 | Musculoskeletal and Neural Physiological Phenomena |
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A physically active intervention group is compared to a physically inactive control group
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Whole body T-score. An arbitrary measure, describing the bone mineral density of the subjects relative to a reference value from 30 year old healthy persons.
| Measurements will be obtained at pre-intervention, (0 weeks), mid intervention (14 weeks) and post intervention (40 weeks) |
| Change in areal bone mineral density of the lumbar spine (L1-L4) | Areal bone mineral density in grams per square centimeter (g/cm2) of the lumbar spine (L1-L4) | Measurement will be obtained at pre-intervention, (0 weeks), mid intervention (14 weeks) and post intervention (40 weeks) |
| Change in T-scores of the lumbar spine (L1-L4) | Lumbar spine (L1-L4) T-score. An arbitrary measure, describing the bone mineral density of the subjects relative to a reference value from 30 year old healthy persons. | Measurement will be obtained at pre-intervention, (0 weeks), mid intervention (14 weeks) and post intervention (40 weeks) |
| Change in areal bone mineral density of the bilateral femur regions | Areal bone mineral density grams per square centimeter (g/cm2) of the bilateral femur regions | Measurement will be obtained at pre-intervention, (0 weeks), mid intervention (14 weeks) and post intervention (40 weeks) |
| Change in T-scores of the bilateral femur regions | T-scores of the bilateral femur regions. An arbitrary measure, describing the bone mineral density of the subjects relative to a reference value from 30 year old healthy persons. | Measurement will be obtained at pre-intervention, (0 weeks), mid intervention (14 weeks) and post intervention (40 weeks) |
| Change in plasma bone turn-over marker (CTX) | Carboxy-terminal collagen crosslinks (CTX), measured as μg/L | Measurement will be obtained at pre-intervention, (0 weeks), mid intervention (14 weeks) and post intervention (40 weeks) |
| Change in Plasma bone turn-over marker (P1NP) | Procollagen type 1 N-terminal propeptide (P1NP), measured as μg/L | Measurement will be obtained at pre-intervention, (0 weeks), mid intervention (14 weeks) and post intervention (40 weeks) |
| Plasma bone turn-over marker (Osteocalcin) | Osteocalcin, measured as μg/L | Measurement will be obtained at pre-intervention, (0 weeks), mid intervention (14 weeks) and post intervention (40 weeks) |
| D013568 | Pathological Conditions, Signs and Symptoms |
| D065886 | Neurodevelopmental Disorders |
| D001523 | Mental Disorders |
| D001519 | Behavior |