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| Name | Class |
|---|---|
| Universität des Saarlandes | OTHER |
| East Suffolk and North Essex NHS Foundation Trust | OTHER |
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Emergency department overcrowding is a major challenge in medicine, leading to a delay in diagnosis and treatment for the patient due to long waiting times. This is very relevant for diseases like acute stroke and other emergencies. The Advanced Mobile Stroke Unit is an ambulance equipped with additional devices to diagnose and treat patients at the emergency site. Patients with less severe conditions can be diagnosed and safely left at home. The objectives of this project are to investigate whether the Advanced Mobile Stroke Unit compared to a normal ambulance enables more accurate triage of patients (treatment at home vs hospital vs specialist vs A&E). The Advanced Mobile Stroke Unit ambulance will be used in a random order of weeks and this will be compared to weeks with normal ambulances. The study will be carried out by the East of England Ambulance Service NHS Trust in collaboration with the East Suffolk and North Essex NHS Foundation Trust in the East of England. The project is a collaboration with Saarland University, Germany,
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Advanced Mobile Stroke Unit | Other | Prehospital treatment of patients with an advanced Mobile Stroke Unit. The advanced Mobile Stroke Unit is an ambulance equipped with a computed tomography scanner, and additional diagnostic devices, such as point-of-care-laboratory and telemedicine to enable the team to diagnose and initiated specialised treatment of emergency patients at the emergency site. |
|
| Conventional ambulance | Other | Prehospital emergency care with conventional ambulances. |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Management | Other | Comparison if different strategies to manage acute emergencies in the pre-hospital setting. |
|
| Measure | Description | Time Frame |
|---|---|---|
| Number of patients requiring hospital attendance within 4h of acute emergency situation | Patient attendance at hospital related to the emergency call (within 4hours) will be assessed | acute emergency situation (4 hours) |
| Measure | Description | Time Frame |
|---|---|---|
| Emergency management metrics | Time metrics related to the emergency call treatment (within 4 hours after call) | acute emergency situation (within 4 hours after call) |
| Clinical Outcome on day 90 |
| Measure | Description | Time Frame |
|---|---|---|
| Safety endpoints | Mortality rate within 90 days | 90 days |
| Safety endpoints | Number of patients with re-contact to EMS within 24h after emergency call |
Inclusion Criteria:
Exclusion Criteria:
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| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Daniel Phillips | Contact | +447971059148 | daniel.phillips@eastamb.nhs.uk | |
| Klaus Fassbender, Prof | Contact | +4968411624103 | klaus.fassbender@uks.eu |
| Name | Affiliation | Role |
|---|---|---|
| Silke Walter, Prof | Universität des Saarlandes, EEAST | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| East of England Ambulance Service NHS Trust | Recruiting | Melbourn | United Kingdom |
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| ID | Term |
|---|---|
| D020521 | Stroke |
| D004630 | Emergencies |
| ID | Term |
|---|---|
| D002561 | Cerebrovascular Disorders |
| D001927 | Brain Diseases |
| D002493 | Central Nervous System Diseases |
| D009422 | Nervous System Diseases |
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| ID | Term |
|---|---|
| D013812 | Therapeutics |
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modified Rankin for patients with brain disease
| 90 days |
| Clinical Outcome on day 90 | EQ-5D5L | 90 days |
| 24 hours |
| Safety endpoints | Number of patients with (serious) adverse events within 90 days | 90 days |
| Health economic analysis | Incremental cost-effectiveness ratio (ICER), treatment costs and health states will be evaluated for each therapy option, for the acute phase (within 12 hours) | acute phase related to the emergency call (12 hours) |
| Health economic analysis | Incremental cost-effectiveness ratio (ICER), treatment costs and health states will be evaluated for each therapy option after 1 year | 1 year after the acute emergency call |
| D014652 | Vascular Diseases |
| D002318 | Cardiovascular Diseases |
| D020969 | Disease Attributes |
| D010335 | Pathologic Processes |
| D013568 | Pathological Conditions, Signs and Symptoms |