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To assess intraocular pressure changes among glaucoma patients on systemic antihypertensive and antihistaminic drugs.
Changes in intraocular pressure in glaucomatous patients with narrow angle may elicit attacks of angle closure glaucoma.
In this study we aim to assess changes in intraocular pressure (IOP) among glaucomatous patients on systemic antihypertensive and antihistaminic drugs.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Antihypertensive drugs group | Changes in IOP among patients on antihypertensive drugs |
| |
| Antihistaminic drugs group | Changes in IOP among patients on antihistaminic drugs |
| |
| Antihypertensive and antihistaminic drugs group | Changes in IOP among patients on both antihypertensive and antihistaminic drugs |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Antihypertensive Agents | Drug | Patients with narrow angle glaucoma and on systemic antihypertensive drugs. |
|
| Measure | Description | Time Frame |
|---|---|---|
| Changes in intraocular pressure (IOP) measured by applanation tonometry | Changes in IOP measured by millimeter mercury (mmHg) | Immediately after visual acuity assessment for each eye after topical anesthetic eye drops and again on one and three months visit |
| Measure | Description | Time Frame |
|---|---|---|
| Changes in pupil diameter | Size of pupil measured in millimeters (mm) 7sing autorefractometer | Immediately after slit lamp examination and again on one and three months visit |
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Inclusion Criteria:
Exclusion Criteria:
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Glaucoma patients regularly visit glaucoma clinic at Banha university, EGYPT
| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Ahmed Abdelshafy, MD | Contact | 01222328766 | ahmad4lg@gmail.com | |
| Marwa Abdelshafy, MD | Contact | 01222328766 | ahmad4lg@gmail.com |
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Ahmed Abdelshafy | Recruiting | Banhā | QA | 13511 | Egypt |
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| ID | Term |
|---|---|
| D015812 | Glaucoma, Angle-Closure |
| D009798 | Ocular Hypertension |
| D006973 | Hypertension |
| ID | Term |
|---|---|
| D005901 | Glaucoma |
| D005128 | Eye Diseases |
| D014652 | Vascular Diseases |
| D002318 | Cardiovascular Diseases |
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| ID | Term |
|---|---|
| D000959 | Antihypertensive Agents |
| D006633 | Histamine Antagonists |
| ID | Term |
|---|---|
| D002317 | Cardiovascular Agents |
| D045506 | Therapeutic Uses |
| D020228 | Pharmacologic Actions |
| D020164 | Chemical Actions and Uses |
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| Antihistaminics | Drug | Patients with narrow angle glaucoma and on systemic antihistaminic drugs. |
|
| D018494 |
| Histamine Agents |
| D018377 | Neurotransmitter Agents |
| D045504 | Molecular Mechanisms of Pharmacological Action |
| D045505 | Physiological Effects of Drugs |