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To compare surgery with definitive chemoradiotherapy for patients with resectable cervical esophageal squamous cell carcinoma.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Surgery | Experimental | Patients receive esophagectomy or neoadjuvant therapy plus esophagectomy |
|
| Definitive chemoradiotherapy | Active Comparator | Patients receive definitive chemoradiotherapy |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Esophagectomy | Procedure | Patients receive esophagectomy or definitive chemoradiotherapy according to patient preference |
|
| Measure | Description | Time Frame |
|---|---|---|
| Overall Survival | 5 year overall survival | 5 years after surgery or definitive Chemoradiotherapy is completed |
| Measure | Description | Time Frame |
|---|---|---|
| Laryngo-esophageal dysfunction free survival | 5 year laryngo-esophageal dysfunction free survival | 5 years after surgery or definitive Chemoradiotherapy is completed |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Zhen Wang, MD | Contact | +8613600892432 | wangzhen@cicams.ac.cn |
| Name | Affiliation | Role |
|---|---|---|
| Jie He, MD | Cancer Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College | Study Director |
| Yin Li, MD | Cancer Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Cancer Hospital Chinese Academy of Medical Sciences | Recruiting | Beijing | China |
expected to be shared as an article paper after the trial ends
expected to be shared as an article paper after the trial ends
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| ID | Term |
|---|---|
| D004938 | Esophageal Neoplasms |
| ID | Term |
|---|---|
| D005770 | Gastrointestinal Neoplasms |
| D004067 | Digestive System Neoplasms |
| D009371 | Neoplasms by Site |
| D009369 | Neoplasms |
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| ID | Term |
|---|---|
| D016629 | Esophagectomy |
| ID | Term |
|---|---|
| D013505 | Digestive System Surgical Procedures |
| D013514 | Surgical Procedures, Operative |
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|
| D006258 |
| Head and Neck Neoplasms |
| D004066 | Digestive System Diseases |
| D004935 | Esophageal Diseases |
| D005767 | Gastrointestinal Diseases |