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| ID | Type | Description | Link |
|---|---|---|---|
| D43TW011302 | U.S. NIH Grant/Contract | View source |
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| Name | Class |
|---|---|
| amfAR, The Foundation for AIDS Research | OTHER |
| National Institutes of Health (NIH) | NIH |
| Fogarty International Center of the National Institute of Health | NIH |
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The study aims to develop and implement a depression screening intervention into routine HIV and sexual health service provision at a transgender health clinic in Thailand, and to explore the facilitators, barriers, feasibility and acceptability of the screening implementation.
The study will follow a mixed-methods approach that will incorporate quantitative and qualitative components. Aim 1 will involve the development and implementation of depression screening intervention at Tangerine Clinic. Aim 2 will involve semi-structured interviews with a purposive subset of participants who received the intervention and healthcare providers to explore the multilevel facilitators, barriers, feasibility and acceptability of the screening implementation. Aim 3 will evaluate the proportion of participants who are offered, accept, and receive the peer-led depression screening intervention, and the proportion who screen positive.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Depression Screening Intervention | Other | All eligible participants will be screened using the Patient Health Questionnaire-2 (PHQ-2) for depression. If screened positive, participants will be further screened with Patient Health Questionnaire-9 (PHQ-9). |
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Depression Screening Intervention | Behavioral | All participants will be screened for depression using PHQ-2 and PHQ-9. Those screened positive for PHQ-2 but decline further screening with PHQ-9 will be assisted for further assessment or care. Those with mild to severe symptoms (score of 7 or higher on PHQ-9) will be assisted for further assessment or care with a psychiatrist. |
| Measure | Description | Time Frame |
|---|---|---|
| Intervention Acceptability: Number of participants who accepted intervention | Acceptability will be measured by the number of clients who were offered and accepted the intervention. | Day 1 |
| Intervention Acceptability: Participants' perspective of the intervention through in-depth interviews | Acceptability will be assessed qualitatively through post-intervention in-depth interviews. | Day 1 |
| Intervention Acceptability: Participants' perspective of the intervention through focus group discussion | Acceptability will be assessed qualitatively through post-intervention focus group discussion. | Day 1 |
| Intervention Feasibility: Number of intervention completed | Feasibility will be measured by number of intervention completed. Point estimates of >50% of participants completed is considered as the minimum criteria for feasibility. | Day 1 |
| Intervention Feasibility: Participants' perspective of the intervention through in-depth interviews | Feasibility will be assessed qualitatively through post-intervention in-depth interviews. | Day 1 |
| Intervention Feasibility: Participants' perspective of the intervention through focus group discussion. | Feasibility will be assessed qualitatively through post-intervention focus group discussion. | Day 1 |
| Number of participants screening positive for depression |
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Inclusion Criteria:
Exclusion Criteria:
1. Transgender women currently receiving care for a mental health diagnosis will be excluded from participating in this study.
Inclusion Criteria for healthcare providers:
Exclusion criteria for healthcare providers
1. Not willing to participate in this study
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| Name | Affiliation | Role |
|---|---|---|
| Rena Janamnuaysook | Institute of HIV Research and Innovation | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Institute of HIV Research and Innovation | Pathum Wan | Bangkok | 10330 | Thailand |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 28158952 | Background | Anand T, Nitpolprasert C, Kerr SJ, Muessig KE, Promthong S, Chomchey N, Hightow-Weidman LB, Chaiyahong P, Phanuphak P, Ananworanich J, Phanuphak N. A qualitative study of Thai HIV-positive young men who have sex with men and transgender women demonstrates the need for eHealth interventions to optimize the HIV care continuum. AIDS Care. 2017 Jul;29(7):870-875. doi: 10.1080/09540121.2017.1286288. Epub 2017 Feb 3. | |
| 31078203 | Background |
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| ID | Term |
|---|---|
| D003863 | Depression |
| ID | Term |
|---|---|
| D001526 | Behavioral Symptoms |
| D001519 | Behavior |
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Screening positive is defined as scoring 7 or greater on PHQ-9. The total possible score for PHQ-9 is 27, with 0-6 being minimum and indicating no depressive symptoms, 7-12 mild depression, 13-18 moderate depression, and 19-27 severe depression. |
| Day 1 |
| Schulman JK, Erickson-Schroth L. Mental Health in Sexual Minority and Transgender Women. Med Clin North Am. 2019 Jul;103(4):723-733. doi: 10.1016/j.mcna.2019.02.005. |
| 14583691 | Background | Kroenke K, Spitzer RL, Williams JB. The Patient Health Questionnaire-2: validity of a two-item depression screener. Med Care. 2003 Nov;41(11):1284-92. doi: 10.1097/01.MLR.0000093487.78664.3C. |
| 27429185 | Background | Poteat T, Scheim A, Xavier J, Reisner S, Baral S. Global Epidemiology of HIV Infection and Related Syndemics Affecting Transgender People. J Acquir Immune Defic Syndr. 2016 Aug 15;72 Suppl 3(Suppl 3):S210-9. doi: 10.1097/QAI.0000000000001087. |
| 28134236 | Background | Rodriguez-Munoz MF, Castelao Legazpi PC, Olivares Crespo ME, Soto Balbuena C, Izquierdo Mendez N, Ferrer Barrientos FJ, Huynh-Nhu L. [PHQ-2 as First Screening Instrument of Prenatal Depression in Primary Health Care, Spain]. Rev Esp Salud Publica. 2017 Jan 30;91:e201701010. Spanish. |
| 33844767 | Background | Martinez P, Soto-Brandt G, Brandt S, Guajardo V, Rojas G. [Validation of patient health Questionnaire-2 to detect depressive symptoms in diabetic or hypertensive patients]. Rev Med Chil. 2020 Nov;148(11):1614-1618. doi: 10.4067/S0034-98872020001101614. Spanish. |
| 23679953 | Background | Baral S, Logie CH, Grosso A, Wirtz AL, Beyrer C. Modified social ecological model: a tool to guide the assessment of the risks and risk contexts of HIV epidemics. BMC Public Health. 2013 May 17;13:482. doi: 10.1186/1471-2458-13-482. |