Lp(a) With CCTA Assessed Parameters and Clinical Outcomes

Association of Lipoprotein (a) With Coronary CTA Assessed High Risk Coronary Disease Attributes and Cardiovascular Outcomes

Lipoprotein(a) [Lp(a)] is a risk factor for cardiovascular events, although the underlying mechanism remains unclear. This study evaluated the relationship between Lp(a) and high-risk attributes (HRA) by coronary computed tomography angiography (CCTA) as well as their prognostic value.

Inclusion Criteria:

• Patients with Lp(a) meaured within 1 week of CCTA examination.

Exclusion Criteria:

• unstable angina pectoris
• acute myocardial infarction
• New York Heart Association class III-IV heart failure
• with a history of bypass surgery
• active infection
• respiratory failure
• chronic kidney disease (estimated glomerular filtration rate [eGFR] <60 ml/min/1.73 m2)
• liver dysfunction (liver enzyme >3 upper reference limit [URL] or bilirubin >2 URL)
• malignancy
• systemic connective tissue disease
• poor CCTA imaging quality not suitable for analysis
• other situations not suitable for the study