We compared the durations of antagonizing and of the severity of effect of sugammadex used in antagonizing the rocuronium in smoker and non-smoker total 40 patients with using Train of Four(TOF) neuromuscular monitorization.

40 patients from American Society of Anesthesiologist (ASA) I- II class, being smokers for at least 10 years or non-smokers, who will undergo elective surgery were included in this randomized prospective study. Patients underwent routine monitoring and neuromuscular monitoring. Propofol 2 mg/kg and intravenous fentanyl 1 mcg/kg were applied at induction. After the loss of eyelash reflex, intravenous rocuronium 0,6 mg/kg was administered. The patient was intubated at a Train of Four count of 2. Anesthesia was continued with 50% O2 + 50% air and sevoflurane 2 % . Rocuronium 0,15 mg/kg was administered when TOF (Train of Four) counter reached 2 during the operation. Sugammadex 2 mg/kg was administered at the end of the operation. The time to reach Train of Four values of 0,7-0,8-0,9 were recorded.

Inclusion Criteria:

• Elective surgery,
• 1-2 according to the ASA ( American Society of Anesthesiologist ) physical status classification.
• Patients who have smoked at least 10 packs or have been smoking for 10 years and currently smoking
• Or never smoked patients

Exclusion Criteria:

• neuromuscular diseases
• radiotherapy and/or chemotherapy anamnesis,
• liver and/or renal disease,
• electrolyte balance,
• history of drug use which affects neuromuscular transmission,
• Body Mass Index (BMI) of more than 27,
• use alcohol