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To determine the phenotype of patients having PMR symptoms and primary Sjogren syndrome (pSS), we used a French national call to identify patients combining both diseases and collected retrospective clinical and biological data.
A national call to identify patients combining pSS and PMR was disseminated in France. Patients with Sjögren's syndrome associated with rheumatoid arthritis were excluded. We described the global population having both diseases and compared them to two historic prospective cohorts of isolated pSS (the prospective cohort of primary Sjögren DiapSS), or isolated PMR (TENOR, a cohort of recent PMR), regarding clinical, imaging and treatments characteristics.
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| Measure | Description | Time Frame |
|---|---|---|
| clinical data | pain (pain scale) | at diagnosis |
| biological data | biology (CRP in mg/L) | at diagnosis |
| biological data | presence of anti-SSA/SSB (yes/no) | at diagnosis |
| histological data | accesories salivary glands biopsies (focus score) | at diagnosis |
| imaging data | US (presence of shoulder involvement yes/no; hip involvement yes/no) | at diagnosis |
| treatments data | use of methotrexate yes/no; abatacept yes/no, rituximab yes/no, corticosteroids yes/no; pilocarpine yes/no; hydroxychloroquine yes/no | at inclusion ( day 0) |
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Inclusion Criteria:
Exclusion Criteria:
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patients fulfilling the ACR/EULAR 2012 criteria for PMR and the ACR/EULAR 2016 criteria for pSS
| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Valerie Devauchelle-Pensec | Contact | +332 9834 7264 | valerie.devauchelle-pensec@chu-brest.fr |
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| CHRU Brest | Recruiting | Brest | 29200 | France |
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| ID | Term |
|---|---|
| D011111 | Polymyalgia Rheumatica |
| D012859 | Sjogren's Syndrome |
| ID | Term |
|---|---|
| D009135 | Muscular Diseases |
| D009140 | Musculoskeletal Diseases |
| D012216 | Rheumatic Diseases |
| D003240 | Connective Tissue Diseases |
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| D017437 | Skin and Connective Tissue Diseases |
| D001172 | Arthritis, Rheumatoid |
| D001168 | Arthritis |
| D007592 | Joint Diseases |
| D014987 | Xerostomia |
| D012466 | Salivary Gland Diseases |
| D009059 | Mouth Diseases |
| D009057 | Stomatognathic Diseases |
| D015352 | Dry Eye Syndromes |
| D007766 | Lacrimal Apparatus Diseases |
| D005128 | Eye Diseases |
| D001327 | Autoimmune Diseases |
| D007154 | Immune System Diseases |