Investigating Myocardial Remodelling in the Failing Human Heart

Investigating Myocardial Remodelling in the Failing Human Heart

Despite improvements in therapy, heart failure is a disease with high mortality and accelerating prevalence. To improve patient care, it is necessary to better understand the features and underlying mechanisms of myocardial remodeling; how it manifests in vivo and its underlying cellular and extracellular changes. The RELAX study will offer insight into myocardial remodeling, by comprehensively assessing function and structure of failing human hearts, and investigate its underlying cellular and extracellular changes.

Inclusion Criteria:

• Eligible for heart transplantation
• Willingness to participate in the present study and ability to understand and sign the written informed consent

Exclusion Criteria:

• Patients under the age of 18.