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In recent years, zirconia-based implant-supported bridge designs have begun to be used more and more as an alternative to metal ceramic bridges. Another new material that has been introduced in the clinic is the high translucent monolithic zirconia, which has only been investigated a few follow-up studies with short follow up duration.
The aim being to evaluate the clinical outcome of implant-anchored posterior bridges, made from
A total of 60 research subjects will be included in the study. Patients in need of a permanent implant-supported bridge, located posterior of the canine in the upper or lower jaw will be asked for participation. Each subject will be treated according to standard treatment protocols with implants from Nobel Biocare, the Branemark implant system and then be randomly assigned to obtain one of the following three type of bridges.
20 research subjects will be included in each of the three study arms. The prosthetic treatment will be carried out according to standard clinic protocol.
All research subjects will be evaluated after 1, 3, 5 years. X-rays and photos will be taken at the installation of the bridges and after 1 and 5 years of follow-up or more frequent, depending on individual indication of the patient and the associated standard clinical care protocol.
Personal data, implant survival, marginal bone loss and biological and technical complications related to the implants will be recorded. Survival of the bridge, technical and biological complication related to the bridge will also be recorded
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| High-translucent monolithic zirconia, | Active Comparator |
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| Zirconia ceramic with porcelain | Active Comparator |
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| Metal ceramics. | Active Comparator |
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| High-translucent monolithic zirconia Bridge | Device | Each patient will be treated according to standard of care with implants from Nobel Biocare, the Branmark system and then randomly assigned to receive a bridge made of either 1) metal ceramic (Nobel Procera, titanium skeleton), 2) zirconia ceramics (Nobel Procera zirconia skeleton) or 3) high-translucent monolithic zirconia (Nobel Procera). |
| Measure | Description | Time Frame |
|---|---|---|
| Complication rate | From placement of prosthetic Bridge until last follow-up of the study after 5 years |
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Inclusion Criteria:
edentulous behind the canine in the maxilla or mandible
Exclusion Criteria:
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| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Jan Kowar | Contact | +46 700 206817 | jan.kowar@vgregion.se |
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| B R Ã… N E M A R K C L I N I C | Recruiting | Gothenburg | 402 33 | Sweden |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 41672962 | Derived | Kowar J, Turri A, Stenport V, Stervik C, Barkarmo S. Comparison of Materials in Implant-Supported Partial Fixed Dental Prostheses: A Randomized Controlled Trial. Clin Implant Dent Relat Res. 2026 Feb;28(1):e70129. doi: 10.1111/cid.70129. |
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| Zirconium oxide ceramics Framework | Device | Each patient will be treated according to standard of care with implants from Nobel Biocare, the Branmark system and then randomly assigned to receive a bridge made of either 1) metal ceramic (Nobel Procera, titanium skeleton), 2) zirconia ceramics (Nobel Procera zirconia skeleton) or 3) high-translucent monolithic zirconia (Nobel Procera). |
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| Metal-ceramic Framework | Device | Each patient will be treated according to standard of care with implants from Nobel Biocare, the Branmark system and then randomly assigned to receive a bridge made of either 1) metal ceramic (Nobel Procera, titanium skeleton), 2) zirconia ceramics (Nobel Procera zirconia skeleton) or 3) high-translucent monolithic zirconia (Nobel Procera). |
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