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| Name | Class |
|---|---|
| Hackensack Meridian Health | OTHER |
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An open label pilot study in mild to moderate AD patients to assess the effects of treatment with ECHS AD pulsed electromagnetic treatment device on disease progression. Enrolled patients will receive active devices. They will treat themselves at home three times a day for 15 minutes over 120 days. Primary end points are the The Alzheimer's Disease Assessment Scale-Cognitive Subscale and the Mini-Mental State Exam. Participants will be followed-up for 9 months post-treatment.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Active ECHS AD device | Experimental | Experimental intervention arm |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| ECHS AD Device | Device | Pulsed electromagnetic therapy device |
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| Measure | Description | Time Frame |
|---|---|---|
| The Alzheimer's Disease Assessment Scale-Cognitive Subscale (ADAS-Cog) | Assessment consisting of 11 tasks, taking up to 30mins, to measure the severity of cognitive dementia symptoms. Score 0-70, Higher number, more severity. | Change between day 0, and 30, 60, 90, 120, 150, 240, 310, 400 days |
| Mini-Mental Status Exam (MMSE) | Clinician assessment of cognitive impairment. Scoring 0-30, lower score, more severity | Change between day 0, and 30, 60, 90, 120, 150, 240, 310, 400 days |
| Global Deterioration questionnaire | Clinician assessment of cognitive impairment. Scored 0-7, higher score, greater severity | Change between day 0, and 30, 60, 90, 120, 150, 240, 310, 400 days |
| Quality of Life Scale | Clinician assessment of cognitive impairment. Scored 0-7, higher score, greater severity | Change between day 0, and 30, 60, 90, 120, 150, 240, 310, 400 days |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Manisha Parulekar, MD | Contact | 551-996-1140 | manisha.parulekar@hmhn.org |
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Hackensack Medical Center | Recruiting | Hackensack | New Jersey | 07601 | United States |
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| ID | Term |
|---|---|
| D000544 | Alzheimer Disease |
| ID | Term |
|---|---|
| D003704 | Dementia |
| D001927 | Brain Diseases |
| D002493 | Central Nervous System Diseases |
| D009422 | Nervous System Diseases |
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Active treatment
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| D024801 |
| Tauopathies |
| D019636 | Neurodegenerative Diseases |
| D019965 | Neurocognitive Disorders |
| D001523 | Mental Disorders |