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Investigator aimed to analyze the clinical efficacy and safety of multiple tracts PCNL as one step therapy to treat the staghorn stones or multiple calyceal calculi which are inaccessible by single tract
Staghorn calculi are branched stones either partial or complete occupying the pelvis and one or more of the renal caliceal system that is detected by non contrast computrized tomography (NCCT) and plain on kidney, ureter, urinary bladder (KUB). An untreated staghorn calculus over time can damage the kidney and deteriorate its function and /or cause life threatening sepsis.
Total stone clearance is an important goal to eradicate any infective focus, relieve obstruction and preserve the kidney function.
Based on American Urological Association (AUA) guideline, PCNL is the most effective, safest and minimally invasive treatment option compared to open surgery
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Multitract PCNL patients | Other | Assessment of the multitract PCNL procedure in removal of large renal stones using pneumatic or laser lithotripsy. |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| PCNL | Procedure | Percutaneous nephrolithotomy ( Extraction of the renal stones using the nephroscope/ Ureteroscope ) |
|
| Measure | Description | Time Frame |
|---|---|---|
| Stone free rate | Assessment of the instant postoperative stone free rate and after one month from the procedure for all 40 participants using the postoperative non contrast computerized tomography (NCCT )and plain on kidney , ureter, urinary bladder (KUB ) | The participants will be followed for one month after the procedure |
| Measure | Description | Time Frame |
|---|---|---|
| Postoperative complications | Measuring the postoperative complications rates, classification of the severity of the complications will assess the safety of the procedure. | From the start of the operation and till one month after the patient discharge. |
| Operative time |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Waleed Mahmoud Abbas, M.Sc | Contact | +2001009377858 | Dr_walidws@yahoo.com | |
| Mohamed Ali Zarzour, MD | Contact | +2001014714142 | Dr-mohamedali81@yahoo.com |
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| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 20811557 | Background | Romero V, Akpinar H, Assimos DG. Kidney stones: a global picture of prevalence, incidence, and associated risk factors. Rev Urol. 2010 Spring;12(2-3):e86-96. | |
| Background | Turk C, Petrik A, Sarica K, et al. Urolithiassis. European Association of Urolgy. Accessed: August 23,2019. | ||
| 27238616 |
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| ID | Term |
|---|---|
| D000069856 | Staghorn Calculi |
| ID | Term |
|---|---|
| D007669 | Kidney Calculi |
| D053040 | Nephrolithiasis |
| D007674 | Kidney Diseases |
| D014570 | Urologic Diseases |
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Measurment of the time from start of the operation till fixation of nephrostomy tube |
| Average of three hours |
| Postoperative pain | Measurment of the postoperative pain score using the Visual analogue scale(VAS) that is divided into mild(1-3), moderate(4-6) and sever(7-10) according to the severity of the pain. | Within 24 hours postoperative and till the patient discharge |
| Hospital stay | Postoperative hospital stay of the participants till thier discharge | Average of six days |
| Background |
| Assimos D, Krambeck A, Miller NL, Monga M, Murad MH, Nelson CP, Pace KT, Pais VM Jr, Pearle MS, Preminger GM, Razvi H, Shah O, Matlaga BR. Surgical Management of Stones: American Urological Association/Endourological Society Guideline, PART I. J Urol. 2016 Oct;196(4):1153-60. doi: 10.1016/j.juro.2016.05.090. Epub 2016 May 27. |
| 26242465 | Background | Zhu W, Liu Y, Liu L, Lei M, Yuan J, Wan SP, Zeng G. Minimally invasive versus standard percutaneous nephrolithotomy: a meta-analysis. Urolithiasis. 2015 Nov;43(6):563-70. doi: 10.1007/s00240-015-0808-y. Epub 2015 Aug 5. |
| D052776 |
| Female Urogenital Diseases |
| D005261 | Female Urogenital Diseases and Pregnancy Complications |
| D000091642 | Urogenital Diseases |
| D052878 | Urolithiasis |
| D014545 | Urinary Calculi |
| D052801 | Male Urogenital Diseases |
| D002137 | Calculi |
| D020763 | Pathological Conditions, Anatomical |
| D013568 | Pathological Conditions, Signs and Symptoms |