The goal of this project is to identify objective, sensitive, and convenient measures for assessing early signs of Parkinson's disease in an at-risk population at home. We will do so by using a wireless sensor and analyzing the radio signals that bounce off patients' bodies, while patients go about their normal life without needing to wear sensors, answer questionnaires, or actively perform any tests.

Inclusion Criteria:

• At least 50 years of age
• Able and willing to provide informed consent
• English fluency
• U.S. resident
• LRRK2 G2019S gene carrier, determined by participation in VALOR-PD
• Mild parkinsonian signs, determined by modified Movement Disorder Society-Unifeid Parkinson's Disease Rating Scale (MDS-UPDRS) score from the most recent VALOR-PD visit
• Have WiFi in their residence
• Access to a smartphone or tablet

Exclusion Criteria:

• Inability to complete study activities, as determined by the study team

• Any medical or psychiatric condition that, in the study team's judgement, would preclude participation

• Self-reported or VALOR-PD investigator determined Parkinson's disease

• Any movement disorder (e.g. essential tremor)

• Currently taking neuroleptics or other drugs known to cause parkinsonism

• Pregnancy

• Non-ambulatory status

• More than one ambulatory pet in the household*

• More than two individuals in the household (not including participant)*

  • these criteria can be waived at the discretion of the investigators

We will enroll LRRK2 G2019S carriers without self-reported or clinician-determined Parkinson's disease (PD) from the VALOR-PD study. VALOR-PD is an observational study following and characterizing a remote, nationwide cohort of LRRK2 G2019S carriers with (n = 59) and without PD (n = 218). Individuals who have a diagnosis of PD will not be eligible to participate, since we aim to explore the device's sensitivity in detecting early symptoms/signs of PD.