Excimer Light in Psoriasis

Excimer Light Effect on Neurogenic Inflammation in Developing Versus Stationary Psoriasis Lesions

The aim of this study is to determine the standard tissue levels of SP and its receptor in lesional skin of psoriasis patients in both developing and stationary stages before and after excimer light therapy.

Inclusion Criteria:

• Type of Psoriasis: plaque psoriasis.
• Less than 10% surface area.

Exclusion Criteria:

• Erythrodermic psoriasis
• Pustular psoriasis
• Topical treatment for psoriasis for the past 2 weeks.
• Systemic retinoids in the last 2 years.
• Systemic treatments (including any drugs that affect SP level as Aprepitant) in the last 3 months.
• Contraindications to excimer light therapy (history of skin malignancy or precancerous conditions like xeroderma pigmentosum or photosensitivity)