Hyperthermia With Flexible Electrode-typed 2-MHz Device During Radiotherapy for Solid Tumors

Exploratory, Open-labelled, Control Group-included, Single Institution Clinical Trial for Evaluating Immunogenic Effect of Hyperthermia Applied With Flexible Electrode-typed 2-MHz Device During Radiotherapy for Solid Tumors

The main purpose of this study is to evaluate immunogenic effect of hyperthermia applied with flexible electrode-typed 2-MHz device during radiotherapy for solid tumors.

Inclusion Criteria:

• Solid tumor (primary, metastatic)
• Eastern Cooperative Oncology Group (ECOG) score 0-3
• Ability to understand and the willingness to sign a written informed consent documents

Exclusion Criteria:

• Myocardial infarct, unstable angina, heart failure, uncontrolled arrhythmia within 6 months
• Active infectious disease
• Pregnant or probability of pregnancy during treatment
• Obesity (BMI ≥35)
• Immunosuppressive drug after organ transplantation
• Autoimmune disease
• Skin injury on treatment area