Effects of Exercise Interventions in Frail Middle-aged and Older Adults

Effects of Exercise Interventions in Frail Middle-aged and Older Adults

This study aimed to determine the ideal parameters of exercise program for frail middle-aged and older adults on physical and mental functions.

Exercise has been suggested as a possible lifestyle intervention for improving physical and cognitive performance. Various training options depending on various physical circumstances will be presented. However, the ideal exercise protocol for frail middle-aged and older adults had the greater benefits remain unknown. In general, 3-6 months of frequent exercise can enhance physical and cognitive outcome.

The investigators conduct this multiple arm, prospective study to determine the ideal parameters of exercise program for frail middle-aged and older adults on physical and cognitive functions. This study designed to recruit 200 older adults with frailty. All the older adults will receive exercise training using either elastic band, dumbbells, machines, treadmill, cycling for 6 months. Outcome measures including a systematic evaluation for frail older persons using comprehensive geriatric assessment, as well as the assessments of physical and cognitive functions before and after interventions.

Inclusion Criteria:

• Patients aged above 50 years old with frailty syndrome

Exclusion Criteria:

• Acute illnesses, such as unstable cardiac dysrhythmia, sepsis, or unstable vital signs
• Physical or Cognitive issues that make it difficult for the patients to participate in our program