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It is a cross sectional observational study. It is to investigate whether AQP-1 polymorphism has any impact on fluid status in hemodialysis patients. The long term stable HD patients in the current center will be enrolled to the study after informed consent. Blood samples will be collected for gene-typing. Fluid status including blood pressure, weekly UF and intra-dialysis body weight change will be collected through their clinical records.
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| observational study, no intervention | Other | observational study, no intervention |
| Measure | Description | Time Frame |
|---|---|---|
| The total ultrafiltration volume in mls from hemodialysis for the whole week of the recruitment | The ultrafiltration volume of each HD section of the enrollment week will be recorded. The total ultrafiltration volume of the week is the primary outcome measure. (In most cases, HD patients have three HD sections per week.) | up to 12 weeks |
| Measure | Description | Time Frame |
|---|---|---|
| The total weight gain in kgs of each HD section of the enrollment | The body weight gain of each HD section of the enrollment week will be recorded. The total body weight gain of the week is the secondary outcome measure. (In most cases, HD patients have three HD sections per week.) | up to 12 weeks |
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Inclusion Criteria:
Exclusion Criteria:
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ESRD patients on maintained hemodialysis.
| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Zanzhe Yu, PhD | Contact | 15901988349 | yuzzhrsd@163.com | |
| Qi Lu, MD | Contact | 68383364 | Luqi@renji.com |
| Name | Affiliation | Role |
|---|---|---|
| Zanzhe Yu, PhD | RenJi Hospital | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Renji Hospital | Shanghai | Shanghai Municipality | 201204 | China |
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| ID | Term |
|---|---|
| D019370 | Observation |
| ID | Term |
|---|---|
| D008722 | Methods |
| D008919 | Investigative Techniques |
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total blood sample stored in local biospecimen facility