patients will be divided into two equal groups, each group including 50 adult patients with a confirmed diagnosis of covid, patients with acute kidney injury, the first group will be treated with early hemodialysis, second group will be conservative until there is an urgent need for dialysis

Inclusion Criteria:

• adult patients (≥18 years old) with confirmed severe acute respiratory syndrome coronavirus 2 infections admitted to the ICU.

Exclusion Criteria:

• •Malignancy.

  • Immuno-deficiency diseases.
  • Chronic diabetic, cardiac and hypertensive patients
  • autoimmune diseases.