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COVID-19 clotting Safety
Covid-19 patients have liability for hyper coagulability, low level laser Therapy improve circulation and decrease liability for hyper coagulability accompanied with circulatory exercises .
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Circulatory exercises group . | Active Comparator | Circulatory exercises. |
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| LLLT group . | Experimental | Low level laser Therapy + circulatory exercises. |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Low level laser Therapy | Radiation | Pin pointed application of low level laser on 15 acupuncture points each point 1 min time of application 15 min. |
|
| Measure | Description | Time Frame |
|---|---|---|
| Circulatory group laboratory investigation. | D-dimerā„.5mg/dL, fibrinogen>2.5mg/dL To examine COVID-19 recovery. | Monthly (an average of two months) |
| Circulatory group: CBC analysis. | Lymphocyte count<1.500mm3, Platelet count<150.000mm3, to examine COVID-19 recovery. | Daily (an average of two months) |
| Circulatory group (PT, PTT). | Prothrombin time>3 sec, activated partial thromboplastin time>5 sec to examine COVID-19 recovery. | Bi weekly (an average of two months) |
| Circulatory group physical examination. | by visual analog scale is horizontal line 100mm length the ends defined as extreme limit of the parameter measured (symptom, pain, health) orientated from the left (the worst) the right (the best) 3 times per week to detect DVT. | Every two days (an average of two months) |
| Circulatory group. BMI. | weight kg on height m2 to detect liability for DVT. | Day one |
| Especially Lab investigation. | C-reactive protein ā„10mg/l for diagnosis of the recovery. | Baseline |
| Measure | Description | Time Frame |
|---|---|---|
| LLLT group laboratory investigation. | D-dimerā„,5mg/dl, fibrinogen>2.5mg/dl, c-reactive proteinā„10mg/dl to examine COVID-19 recovery. Fibrinogen | Monthly (an average of two months) |
| LLLT group CBC analysis. |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Enas Dr Ahmed, BSC | Contact | 01028406164 | Therapist | enaswagdydaib@gmail.com |
| Name | Affiliation | Role |
|---|---|---|
| Enas Dr Ahmed, BSC | Physical therapy faculty CairoU. | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Physical therapy faculty | Recruiting | Dokki | Giza Governorate | 12611 | Egypt |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 10805940 | Background | Agaiby AD, Ghali LR, Wilson R, Dyson M. Laser modulation of angiogenic factor production by T-lymphocytes. Lasers Surg Med. 2000;26(4):357-63. doi: 10.1002/(sici)1096-9101(2000)26:43.0.co;2-o. | |
| 32232218 | Background | Emami A, Javanmardi F, Pirbonyeh N, Akbari A. Prevalence of Underlying Diseases in Hospitalized Patients with COVID-19: a Systematic Review and Meta-Analysis. Arch Acad Emerg Med. 2020 Mar 24;8(1):e35. eCollection 2020. |
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| ID | Term |
|---|---|
| D028022 | Low-Level Light Therapy |
| ID | Term |
|---|---|
| D053685 | Laser Therapy |
| D013812 | Therapeutics |
| D010789 | Phototherapy |
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Two groups of 30 patients, 1st circulatory exercise, 2nd LLLT and circulatory exercises.
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circulatory exercise only, circulatory exercises and LLLT.
| Circulatory exercises | Other | Active assisted or against mild resistance. Supine with leg up position 18degrees measured by the bed water balance in side rails. If patient is not comfortable according to the modified Borg scale or contra indicated for the position then assume the supine position. The subject will have A 3 min rest period to acclimatize themselves to each position. The ankle pumping exercises consisted of simple repetitions of dorsiflexion 1 sec and planter- flexion for 1 sec with three different exercise intervals:
Subjects will have practiced ankle pumps before the exercise to get familiar and be educated about the procedure. |
|
lymphocyte count<1,500mm3, platelet count<150,000mm3, for examine COVID-19 recovery.
| Daily (an average of two months) |
| LLLT group. {PTT, PT}. | Prothrombin time>3 sec, activated partial thromboplastin time>5sec to examine COVID-19 recovery. | Bi weekly (an average of two months) |
| LLLT group physical examination. | by visual analog scale is a straight horizontal line of fixed length 100mm the end is extreme limit of the parameter measured (symptom, pain, health) orientated from the left (the worst) to the right (the best) 3times per week to detect DVT. | Every two days (an average of two months) |
| LLLT group. BMI. | Weight kg/height m2 to detect liability for DVT. | Day one |
| Specifically Lab investigation. | C_reactive proteinā„10mg/l.help diagnosis of the recovery. | Baseline |
| Background | ConnorsJ.M.,LevyJ.H(2020).Thromboinflammation and the hyper coagulability of COVID-19.JThromb Haemost https://doi.org/10.1111/jth.14849. |